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Stress-induced epigenetic transcriptional memory of acetylcholinesterase by HDAC4

Stress induces long-lasting changes in neuronal gene expression and cholinergic neurotransmission, but the underlying mechanism(s) are incompletely understood. Here, we report that chromatin structure and histone modifications are causally involved in this transcriptional memory. Specifically, the A...

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Detalhes bibliográficos
Main Authors: Sailaja, Badi Sri, Cohen-Carmon, Dorit, Zimmerman, Gabriel, Soreq, Hermona, Meshorer, Eran
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3535662/
https://ncbi.nlm.nih.gov/pubmed/23236169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1209990110
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