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Polyglutamine (polyQ) disorders: The chromatin connection
Polyglutamine (PolyQ)-related diseases are dominant late-onset genetic disorders that are manifested by progressive neurodegeneration, leading to behavioral and physical impairments. An increased body of evidence suggests that chromatin structure and epigenetic regulation are involved in disease pat...
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Landes Bioscience
2012
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3474664/ https://ncbi.nlm.nih.gov/pubmed/22892726 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/nucl.21481 |
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