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Stress-induced epigenetic transcriptional memory of acetylcholinesterase by HDAC4

Stress induces long-lasting changes in neuronal gene expression and cholinergic neurotransmission, but the underlying mechanism(s) are incompletely understood. Here, we report that chromatin structure and histone modifications are causally involved in this transcriptional memory. Specifically, the A...

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Bibliographische Detailangaben
Hauptverfasser: Sailaja, Badi Sri, Cohen-Carmon, Dorit, Zimmerman, Gabriel, Soreq, Hermona, Meshorer, Eran
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3535662/
https://ncbi.nlm.nih.gov/pubmed/23236169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1209990110
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