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αIIbβ3 biogenesis is controlled by engagement of αIIb in the calnexin cycle via the N15-linked glycan

Although much is known about αIIbβ3 structure and function, relatively little is understood about its biogenesis. Thus, we studied the kinetics of pro-αIIb production and degradation, focusing on whether proteasomal degradation or the calnexin cycle participates in these processes. In pulse-chase an...

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Detalhes bibliográficos
Main Authors: Mitchell, W. Beau, Li, JiHong, French, Deborah L., Coller, Barry S.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society of Hematology 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895385/
https://ncbi.nlm.nih.gov/pubmed/16304048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-07-2990
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