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αIIbβ3 biogenesis is controlled by engagement of αIIb in the calnexin cycle via the N15-linked glycan
Although much is known about αIIbβ3 structure and function, relatively little is understood about its biogenesis. Thus, we studied the kinetics of pro-αIIb production and degradation, focusing on whether proteasomal degradation or the calnexin cycle participates in these processes. In pulse-chase an...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The American Society of Hematology
2006
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1895385/ https://ncbi.nlm.nih.gov/pubmed/16304048 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-07-2990 |
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