Synthesis and Evaluation in Monkey of [(18)F]4-Fluoro-N-methyl-N-(4-(6- (methylamino)pyrimidin-4-yl)thiazol-2-yl)benzamide ([(18)F]FIMX), a Promising Radioligand for PET Imaging of...

Por Xu, Rong, Zanotti-Fregonara, Paolo, Zoghbi, Sami S., Gladding, Robert L., Woock, Alicia, Innis, Robert B., Pike, Victor W
Publicado em 2013

Synthesis and characterization in monkey of [(11)C]SP203 as a radioligand for imaging brain metabotropic glutamate 5 receptors

Por Siméon, Fabrice G., Liow, Jeih-San, Zhang, Yi, Hong, Jinsoo, Gladding, Robert L., Zoghbi, Sami S., Innis, Robert B., Pike, Victor W.
Publicado no Eur J Nucl Med Mol Imaging (2012)

Kinetic analysis in human brain of [(11)C](R)-rolipram, a positron emission tomographic radioligand to image phosphodiesterase 4: a retest study and use of an image-derived input f...

Por Zanotti-Fregonara, Paolo, Zoghbi, Sami S., Liow, Jeih-San, Luong, Elise, Boellaard, Ronald, Gladding, Robert L., Pike, Victor W., Innis, Robert B., Fujita, Masahiro
Publicado em 2010

Radiosynthesis and evaluation of an (18)F-labeled positron emission tomography (PET) radioligand for brain histamine subtype-3 receptors based on a nonimidazole 2-aminoethylbenzofu...

Por Bao, Xiaofeng, Lu, Shuiyu, Liow, Jeih-San, Zoghbi, Sami S., Jenko, Kimberly J., Clark, David T., Gladding, Robert L., Innis, Robert B., Pike, Victor W.
Publicado em 2012

Synthesis and Evaluation of [N-methyl-(11)C]N-Desmethyl-loperamide as a New and Improved PET Radiotracer for Imaging P-gp Function

Por Lazarova, Neva, Zoghbi, Sami S., Hong, Jinsoo, Seneca, Nicholas, Tuan, Ed, Gladding, Robert L., Liow, Jeih-San, Taku, Andrew, Innis, Robert B., Pike, Victor W.
Publicado em 2008

P-Glycoprotein Function at the Blood-Brain Barrier Imaged in Monkey with (11)C-N-Desmethyl-Loperamide

Por Liow, Jeih-San, Kreisl, William, Zoghbi, Sami S., Lazarova, Neva, Seneca, Nicholas, Gladding, Robert L., Taku, Andrew, Herscovitch, Peter, Pike, Victor W., Innis, Robert B.
Publicado em 2008

Human Brain Imaging and Radiation Dosimetry of (11)C-N-Desmethyl-Loperamide, a PET Radiotracer to Measure the Function of P-Glycoprotein

Por Seneca, Nicholas, Zoghbi, Sami S., Liow, Jeih-San, Kreisl, William, Herscovitch, Peter, Jenko, Kimberly, Gladding, Robert L., Taku, Andrew, Pike, Victor W., Innis, Robert B.
Publicado em 2009

In vitro and in vivo evaluation of (11)C-SD5024, a novel PET radioligand for human brain imaging of cannabinoid CB(1) receptors

Por Tsujikawa, Tetsuya, Zoghbi, Sami S., Hong, Jinsoo, Donohue, Sean R., Jenko, Kimberly J., Gladding, Robert L., Halldin, Christer, Pike, Victor W., Innis, Robert B., Fujita, Masahiro
Publicado em 2013

(11)C-CUMI-101, a PET Radioligand, Behaves as a Serotonin 1A Receptor Antagonist and Also Binds to α(1) Adrenoceptors in Brain

Por Shrestha, Stal Saurav, Liow, Jeih-San, Lu, Shuiyu, Jenko, Kimberly, Gladding, Robert L., Svenningsson, Per, Morse, Cheryl L., Zoghbi, Sami S., Pike, Victor W., Innis, Robert B.
Publicado no J Nucl Med (2014)

Evaluation in Monkey of Two Candidate PET Radioligands, [(11)C]RX-1 and [(18)F]RX-2, for Imaging Brain 5-HT(4) Receptors

Por LOHITH, TALAKAD G., XU, RONG, TSUJIKAWA, TETSUYA, MORSE, CHERYL L., ANDERSON, KACEY B., GLADDING, ROBERT L., ZOGHBI, SAMI S., FUJITA, MASAHIRO, INNIS, ROBERT B., PIKE, VICTOR W.
Publicado no Synapse (2014)

[carbonyl-(11)C]4-Fluoro-N-methyl-N-(4-(6-(methylamino)pyrimidin-4-yl)thiazol-2-yl)benzamide ([(11)C]FIMX) is an effective radioligand for PET imaging of metabotropic glutamate rec...

Por Hong, Jinsoo, Lu, Shuiyu, Xu, Rong, Liow, Jeih-San, Woock, Alicia E., Jenko, Kimberly J., Gladding, Robert L., Zoghbi, Sami S., Innis, Robert B., Pike, Victor W.
Publicado no Nucl Med Biol (2015)

The PET Radioligand (18)F-FIMX Images and Quantifies Metabotropic Glutamate Receptor 1 in Proportion to the Regional Density of Its Gene Transcript in Human Brain

Por Zanotti-Fregonara, Paolo, Xu, Rong, Zoghbi, Sami S., Liow, Jeih-San, Fujita, Masahiro, Veronese, Mattia, Gladding, Robert L., Rallis-Frutos, Denise, Hong, Jinsoo, Pike, Victor W., Innis, Robert B.
Publicado no J Nucl Med (2015)

Kinetic Brain Analysis and Whole-Body Imaging in Monkey of [(11)C]MNPA: A Dopamine Agonist Radioligand

Por SENECA, NICHOLAS, SKINBJERG, METTE, ZOGHBI, SAMI S., LIOW, JEIH-SAN, GLADDING, ROBERT L., HONG, JINSOO, KANNAN, PAVITRA, TUAN, EDWARD, SIBLEY, DAVID R., HALLDIN, CHRISTER, PIKE, VICTOR W., INNIS, ROBERT B.
Publicado em 2008

[O-methyl-(11)C]N-(4-(4-(3-Chloro-2-methoxyphenyl)-piperazin-1-yl)butyl)-1H-indole-2-carboxamide ([(11)C]BAK4-51) Is an Efflux Transporter Substrate and Ineffective for PET Imaging...

Por Liow, Jeih-San, Morse, Cheryl L., Lu, Shuiyu, Frankland, Michael, Tye, George L., Zoghbi, Sami S., Gladding, Robert L., Shaik, Anver B., Innis, Robert B., Newman, Amy H., Pike, Victor W.
Publicado no Molecules (2018)

(11)C-LY2428703, a positron emission tomographic radioligand for the metabotropic glutamate receptor 1, is unsuitable for imaging in monkey and human brains

Por Zanotti-Fregonara, Paolo, Barth, Vanessa N, Zoghbi, Sami S, Liow, Jeih-San, Nisenbaum, Eric, Siuda, Edward, Gladding, Robert L, Rallis-Frutos, Denise, Morse, Cheryl, Tauscher, Johannes, Pike, Victor W, Innis, Robert B
Publicado em 2013

Synthesis and Evaluation of Translocator 18 kDa Protein (TSPO) Positron Emission Tomography (PET) Radioligands with Low Binding Sensitivity to Human Single Nucleotide Polymorphism...

Por Zanotti-Fregonara, Paolo, Zhang, Yi, Jenko, Kimberly J., Gladding, Robert L., Zoghbi, Sami S., Fujita, Masahiro, Sbardella, Gianluca, Castellano, Sabrina, Taliani, Sabrina, Martini, Claudia, Innis, Robert B., Da Settimo, Federico, Pike, Victor W.
Publicado em 2014

Comparison of [(11)C]-(R)-PK 11195 and [(11)C]PBR28, Two Radioligands for Translocator Protein (18 kDa) in Human and Monkey: Implications for Positron Emission Tomographic Imaging...

Por Kreisl, William C., Fujita, Masahiro, Fujimura, Yota, Kimura, Nobuyo, Jenko, Kimberly J., Kannan, Pavitra, Hong, Jinsoo, Morse, Cheryl L., Zoghbi, Sami S., Gladding, Robert L., Jacobson, Steven, Oh, Unsong, Pike, Victor W., Innis, Robert B.
Publicado em 2009

Brain and Whole-Body Imaging in Rhesus Monkeys of (11)C-NOP-1A, a Promising PET Radioligand for Nociceptin/Orphanin FQ Peptide Receptors

Por Kimura, Yasuyuki, Fujita, Masahiro, Hong, Jinsoo, Lohith, Talakad G., Gladding, Robert L., Zoghbi, Sami S., Tauscher, Johannes A., Goebl, Nancy, Rash, Karen S., Chen, Zhaogen, Pedregal, Concepcion, Barth, Vanessa N., Pike, Victor W., Innis, Robert B.
Publicado em 2011

Evaluation of Two Potent and Selective PET Radioligands to Image COX-1 and COX-2 in Rhesus Monkeys

Por Kim, Min-Jeong, Shrestha, Stal S., Cortes, Michelle, Singh, Prachi, Morse, Cheryl, Liow, Jeih-San, Gladding, Robert L., Brouwer, Chad, Henry, Katharine, Gallagher, Evan, Tye, George L., Zoghbi, Sami S., Fujita, Masahiro, Pike, Victor W., Innis, Robert B.
Publicado no J Nucl Med (2018)