Brain and Whole-Body Imaging of Nociceptin/Orphanin FQ Peptide Receptor in Humans Using the PET Ligand (11)C-NOP-1A

Tekijä Lohith, Talakad G., Zoghbi, Sami S., Morse, Cheryl L., Araneta, Maria F., Barth, Vanessa N., Goebl, Nancy A., Tauscher, Johannes T., Pike, Victor W., Innis, Robert B., Fujita, Masahiro
Julkaistu 2012

Retest imaging of [(11)C]NOP-1A binding to nociceptin/orphanin FQ peptide (NOP) receptors in brain of healthy humans

Tekijä Lohith, Talakad G., Zoghbi, Sami S., Morse, Cheryl L., Araneta, Maria D. Ferraris, Barth, Vanessa N., Goebl, Nancy A., Tauscher, Johannes T., Pike, Victor W., Innis, Robert B., Fujita, Masahiro
Julkaistu 2013

Design, synthesis, and evaluation of hydroxamic acid-based molecular probes for in vivo imaging of histone deacetylase (HDAC) in brain

Tekijä Wang, Changning, Eessalu, Thomas E, Barth, Vanessa N, Mitch, Charles H, Wagner, Florence F, Hong, Yijia, Neelamegam, Ramesh, Schroeder, Frederick A, Holson, Edward B, Haggarty, Stephen J, Hooker, Jacob M
Julkaistu 2013

(11)C-LY2428703, a positron emission tomographic radioligand for the metabotropic glutamate receptor 1, is unsuitable for imaging in monkey and human brains

Tekijä Zanotti-Fregonara, Paolo, Barth, Vanessa N, Zoghbi, Sami S, Liow, Jeih-San, Nisenbaum, Eric, Siuda, Edward, Gladding, Robert L, Rallis-Frutos, Denise, Morse, Cheryl, Tauscher, Johannes, Pike, Victor W, Innis, Robert B
Julkaistu 2013

Identification and pharmacological profile of SPP1, a potent, functionally selective and brain penetrant agonist at muscarinic M(1) receptors

Tekijä Broad, Lisa M, Sanger, Helen E, Mogg, Adrian J, Colvin, Ellen M, Zwart, Ruud, Evans, David A, Pasqui, Francesca, Sher, Emanuele, Wishart, Graham N, Barth, Vanessa N, Felder, Christian C, Goldsmith, Paul J
Julkaisussa Br J Pharmacol (2018)

Brain and Whole-Body Imaging in Rhesus Monkeys of (11)C-NOP-1A, a Promising PET Radioligand for Nociceptin/Orphanin FQ Peptide Receptors

Tekijä Kimura, Yasuyuki, Fujita, Masahiro, Hong, Jinsoo, Lohith, Talakad G., Gladding, Robert L., Zoghbi, Sami S., Tauscher, Johannes A., Goebl, Nancy, Rash, Karen S., Chen, Zhaogen, Pedregal, Concepcion, Barth, Vanessa N., Pike, Victor W., Innis, Robert B.
Julkaistu 2011

Synthesis and Evaluation of Radioligands for Imaging Brain Nociceptin/Orphanin FQ Peptide (NOP) Receptors with Positron Emission Tomography

Tekijä Pike, Victor W., Rash, Karen S., Chen, Zhaogen, Pedregal, Concepción, Statnick, Michael A., Kimura, Yasuyuki, Hong, Jinsoo, Zoghbi, Sami S., Fujita, Masahiro, Toledo, Miguel A., Diaz, Nuria, Gackenheimer, Susan L., Tauscher, Johannes T., Barth, Vanessa N., Innis, Robert B.
Julkaistu 2011

Pseudoreference Regions for Glial Imaging with (11)C-PBR28: Investigation in 2 Clinical Cohorts

Tekijä Albrecht, Daniel S., Normandin, Marc D., Shcherbinin, Sergey, Wooten, Dustin W., Schwarz, Adam J., Zürcher, Nicole R., Barth, Vanessa N., Guehl, Nicolas J., Akeju, Oluwaseun, Atassi, Nazem, Veronese, Mattia, Turkheimer, Federico, Hooker, Jacob M., Loggia, Marco L.
Julkaisussa J Nucl Med (2018)

In Vitro Pharmacological Characterization and In Vivo Validation of LSN3172176 a Novel M1 Selective Muscarinic Receptor Agonist Tracer Molecule for Positron Emission Tomography

Tekijä Mogg, Adrian J., Eessalu, Thomas, Johnson, Megan, Wright, Rebecca, Sanger, Helen E., Xiao, Hongling, Crabtree, Michael G., Smith, Alex, Colvin, Ellen M., Schober, Douglas, Gehlert, Donald, Jesudason, Cynthia, Goldsmith, Paul J., Johnson, Michael P., Felder, Christian C., Barth, Vanessa N., Broad, Lisa M.
Julkaisussa J Pharmacol Exp Ther (2018)

Evaluation in vitro and in animals of a new (11)C-labeled PET radioligand for metabotropic glutamate receptors 1 in brain

Tekijä Zanotti-Fregonara, Paolo, Barth, Vanessa N., Liow, Jeih-San, Zoghbi, Sami S., Clark, David T., Rhoads, Emily, Siuda, Edward, Heinz, Beverly A., Nisenbaum, Eric, Dressman, Bruce, Joshi, Elizabeth, Luffer-Atlas, Debra, Fisher, Matthew J., Masters, John J., Goebl, Nancy, Kuklish, Steven L., Morse, Cheryl, Tauscher, Johannes, Pike, Victor W., Innis, Robert B.
Julkaistu 2012

Evaluation of a PET Radioligand to Image O-GlcNAcase in Brain and Periphery of Rhesus Monkey and Knock-Out Mouse

Tekijä Paul, Soumen, Haskali, Mohammad B., Liow, Jeih-San, Zoghbi, Sami S., Barth, Vanessa N., Kolodrubetz, Marcy Comly, Bond, Michelle R., Morse, Cheryl L., Gladding, Robert L., Frankland, Michael P., Kant, Nancy, Slieker, Lawrence, Shcherbinin, Sergey, Nuthall, Hugh N., Zanotti-Fregonara, Paolo, Hanover, John A., Jesudason, Cynthia, Pike, Victor W., Innis, Robert B.
Julkaisussa J Nucl Med (2019)

Biased M1-muscarinic-receptor-mutant mice inform the design of next-generation drugs

Tekijä Bradley, Sophie J., Molloy, Colin, Valuskova, Paulina, Dwomoh, Louis, Scarpa, Miriam, Rossi, Mario, Finlayson, Lisa, Svensson, Kjell A., Chernet, Eyassu, Barth, Vanessa N., Gherbi, Karolina, Sykes, David A., Wilson, Caroline A., Mistry, Rajendra, Sexton, Patrick M., Christopoulos, Arthur, Mogg, Adrian J., Rosethorne, Elizabeth M., Sakata, Shuzo, Challiss, R. A. John, Broad, Lisa M., Tobin, Andrew B.
Julkaisussa Nat Chem Biol (2020)

Preclinical findings predicting efficacy and side‐effect profile of LY2940094, an antagonist of nociceptin receptors

Tekijä Witkin, Jeffrey M., Rorick‐Kehn, Linda M., Benvenga, Mark J., Adams, Benjamin L., Gleason, Scott D., Knitowski, Karen M., Li, Xia, Chaney, Steven, Falcone, Julie F., Smith, Janice W., Foss, Julie, Lloyd, Kirsti, Catlow, John T., McKinzie, David L., Svensson, Kjell A., Barth, Vanessa N., Toledo, Miguel A., Diaz, Nuria, Lafuente, Celia, Jiménez, Alma, Benito, Alfonso, Pedregal, Conception, Martínez‐Grau, Maria A., Post, Anke, Ansonoff, Michael A., Pintar, John E., Statnick, Michael A.
Julkaisussa Pharmacol Res Perspect (2016)