Image-derived input function for brain PET studies: many challenges and few opportunities

le Zanotti-Fregonara, Paolo, Chen, Kewei, Liow, Jeih-San, Fujita, Masahiro, Innis, Robert B
Foilsithe 2011

The 5-HT(1A) Receptor PET Radioligand (11)C-CUMI-101 Has Significant Binding to α(1)-Adrenoceptors in Human Cerebellum, Limiting Its Use as a Reference Region

le Shrestha, Stal S., Liow, Jeih-San, Jenko, Kimberly, Ikawa, Masamichi, Zoghbi, Sami S., Innis, Robert B.
Foilsithe in J Nucl Med (2016)

Evaluation of [(11)C]S14506 and [(18)F]S14506 in rat and monkey as agonist PET radioligands for brain 5-HT(1A) receptors

le Lu, Shuiyu, Liow, Jeih-San, Zoghbi, Sami S., Hong, Jinsoo, Innis, Robert B., Pike, Victor W.
Foilsithe 2010

Whole-Body Biodistribution and Radiation Dosimetry in Monkeys and Humans of the Phosphodiesterase 4 Radioligand [(11)C](R)-Rolipram: Comparison of 2-Dimensional Planar, Bisected, a...

le Sprague, David R., Fujita, Masahiro, Ryu, Yong Hoon, Liow, Jeih-San, Pike, Victor W., Innis, Robert B.
Foilsithe 2008

The Evaluation of Dynamic FDG-PET for Detecting Epileptic Foci and Analyzing Reduced Glucose Phosphorylation in Refractory Epilepsy

le Tang, Yongxiang, Liow, Jeih-San, Zhang, Zhimin, Li, Jian, Long, Tingting, Li, Yulai, Tang, Beisha, Hu, Shuo
Foilsithe in Front Neurosci (2019)

Human Biodistribution and Dosimetry of (11)C-CUMI-101, an Agonist Radioligand for Serotonin-1A Receptors in Brain

le Hines, Christina S., Liow, Jeih-San, Zanotti-Fregonara, Paolo, Hirvonen, Jussi, Morse, Cheryl, Pike, Victor W., Innis, Robert B.
Foilsithe 2011

Application of Calibrated Image Derived Input Function to a Clinical Protocol

le Zanotti-Fregonara, Paolo, Lyoo, Chul Hyoung, Bar-Hen, Avner, Liow, Jeih-San, Zoghbi, Sami S, Fujita, Masahiro, Innis, Robert B.
Foilsithe 2014

[(11)C]Rhodamine-123: synthesis and biodistribution in rodents

le Bao, Xiaofeng, Lu, Shuiyu, Liow, Jeih-San, Morse, Cheryl L., Anderson, Kacey, Zoghbi, Sami S., Innis, Robert B., Pike, Victor W.
Foilsithe 2012

Image-derived input function in PET brain studies: blood-based methods are resistant to motion artifacts

le Zanotti-Fregonara, Paolo, Liow, Jeih-San, Comtat, Claude, Zoghbi, Sami S., Zhang, Yi, Pike, Victor W., Fujita, Masahiro, Innis, Robert B.
Foilsithe 2012

Whole-body biodistribution and radiation dosimetry estimates for the PET dopamine transporter probe (18)F-FECNT in non-human primates

le Tipre, Dnyanesh N., Fujita, Masahiro, Chin, Frederick T., Seneca, Nicholas, Vines, Douglas, Liow, Jeih-San, Pike, Victor W., Innis, Robert B.
Foilsithe 2004

Synthesis and characterization in monkey of [(11)C]SP203 as a radioligand for imaging brain metabotropic glutamate 5 receptors

le Siméon, Fabrice G., Liow, Jeih-San, Zhang, Yi, Hong, Jinsoo, Gladding, Robert L., Zoghbi, Sami S., Innis, Robert B., Pike, Victor W.
Foilsithe in Eur J Nucl Med Mol Imaging (2012)

Neuroinflammation in neocortical epilepsy measured by PET imaging of translocator protein

le Dickstein, Leah P., Liow, Jeih-San, Austermuehle, Alison, Zoghbi, Sami, Inati, Sara K., Zaghloul, Kareem, Zanotti-Fregonara, Paolo, Theodore, William H.
Foilsithe in Epilepsia (2019)

Radiodefluorination of 3-Fluoro-5-(2-(2-[(18)F](fluoromethyl)thiazol-4-yl)ethynyl)benzonitrile ([(18)F]SP203), a Radioligand for Imaging Brain Metabotropic Glutamate Subtype-5 Rece...

le Shetty, H. Umesha, Zoghbi, Sami S., Siméon, Fabrice G., Liow, Jeih-San, Brown, Amira K., Kannan, Pavitra, Innis, Robert B., Pike, Victor W.
Foilsithe 2008

Dopamine β-hydroxylase-deficient mice have normal densities of D(2) dopamine receptors in the high affinity state based on in vivo PET imaging and in vitro radioligand binding

le Skinbjerg, Mette, Seneca, Nicholas, Liow, Jeih-San, Hong, Jinsoo, Weinshenker, David, Pike, Victor W., Halldin, Christer, Sibley, David R., Innis, Robert B.
Foilsithe 2010

Occupancy of Dopamine D(2/3) Receptors in Rat Brain by Endogenous Dopamine Measured With the Agonist Positron Emission Tomography Radioligand [(11)C]MNPA

le SENECA, NICHOLAS, ZOGHBI, SAMI S., SKINBJERG, METTE, LIOW, JEIH-SAN, HONG, JINSOO, SIBLEY, DAVID R., PIKE, VICTOR W., HALLDIN, CHRISTER, INNIS, ROBERT B.
Foilsithe 2008

P-glycoprotein function at the blood-brain barrier in humans can be quantified with the substrate radiotracer (11)C-N-desmethyl-loperamide

le Kreisl, William C., Liow, Jeih-San, Kimura, Nobuyo, Seneca, Nicholas, Zoghbi, Sami S., Morse, Cheryl L., Herscovitch, Peter, Pike, Victor W., Innis, Robert B.
Foilsithe 2010

Kinetic analysis in human brain of [(11)C](R)-rolipram, a positron emission tomographic radioligand to image phosphodiesterase 4: a retest study and use of an image-derived input f...

le Zanotti-Fregonara, Paolo, Zoghbi, Sami S., Liow, Jeih-San, Luong, Elise, Boellaard, Ronald, Gladding, Robert L., Pike, Victor W., Innis, Robert B., Fujita, Masahiro
Foilsithe 2010

Radiosynthesis and evaluation of an (18)F-labeled positron emission tomography (PET) radioligand for brain histamine subtype-3 receptors based on a nonimidazole 2-aminoethylbenzofu...

le Bao, Xiaofeng, Lu, Shuiyu, Liow, Jeih-San, Zoghbi, Sami S., Jenko, Kimberly J., Clark, David T., Gladding, Robert L., Innis, Robert B., Pike, Victor W.
Foilsithe 2012

Cerebellum can serve as a pseudo-reference region in Alzheimer’s disease to detect neuroinflammation measured with PET radioligand binding to translocator protein (TSPO)

le Lyoo, Chul Hyoung, Ikawa, Masamichi, Liow, Jeih-San, Zoghbi, Sami S., Morse, Cheryl, Pike, Victor W., Fujita, Masahiro, Innis, Robert B., Kreisl, William Charles
Foilsithe in J Nucl Med (2015)

Synthesis and Evaluation of [N-methyl-(11)C]N-Desmethyl-loperamide as a New and Improved PET Radiotracer for Imaging P-gp Function

le Lazarova, Neva, Zoghbi, Sami S., Hong, Jinsoo, Seneca, Nicholas, Tuan, Ed, Gladding, Robert L., Liow, Jeih-San, Taku, Andrew, Innis, Robert B., Pike, Victor W.
Foilsithe 2008