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Synthesis and characterization in monkey of [(11)C]SP203 as a radioligand for imaging brain metabotropic glutamate 5 receptors
PURPOSE: [(18)F]SP203 (3-fluoro−5-(2− (2-([(18)F]fluoromethyl)-thiazol−4-yl)ethynyl)benzonitrile) is an effective high-affinity and selective radioligand for imaging metabotropic 5 receptors (mGluR5) in human brain with PET. To provide a radioligand that may be used for more than one scanning sessio...
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| Publicado no: | Eur J Nucl Med Mol Imaging |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5577640/ https://ncbi.nlm.nih.gov/pubmed/22885775 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00259-012-2205-x |
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