Development of N-Methyl-(2-arylquinolin-4-yl)oxypropanamides as Leads to PET Radioligands for Translocator Protein (18 kDa)

por Brouwer, Chad, Jenko, Kimberly, Zoghbi, Sami S., Innis, Robert B., Pike, Victor W.
Publicado 2014

The 5-HT(1A) Receptor PET Radioligand (11)C-CUMI-101 Has Significant Binding to α(1)-Adrenoceptors in Human Cerebellum, Limiting Its Use as a Reference Region

por Shrestha, Stal S., Liow, Jeih-San, Jenko, Kimberly, Ikawa, Masamichi, Zoghbi, Sami S., Innis, Robert B.
Publicado en J Nucl Med (2016)

Evaluation of [(11)C]S14506 and [(18)F]S14506 in rat and monkey as agonist PET radioligands for brain 5-HT(1A) receptors

por Lu, Shuiyu, Liow, Jeih-San, Zoghbi, Sami S., Hong, Jinsoo, Innis, Robert B., Pike, Victor W.
Publicado 2010

Plasma radiometabolite correction in dynamic PET studies: Insights on the available modeling approaches

por Tonietto, Matteo, Rizzo, Gaia, Veronese, Mattia, Fujita, Masahiro, Zoghbi, Sami S, Zanotti-Fregonara, Paolo, Bertoldo, Alessandra
Publicado en J Cereb Blood Flow Metab (2015)

IN VIVO BINDING OF PROTOPORPHYRIN IX TO RAT TRANSLOCATOR PROTEIN IMAGED WITH POSITRON EMISSION TOMOGRAPHY

por Ozaki, Harushige, Zoghbi, Sami S., Hong, Jinsoo, Verma, Ajay, Pike, Victor W., Innis, Robert B., Fujita, Masahiro
Publicado 2010

N′-3-(Trifluoromethyl)phenyl Derivatives of N-Aryl-N′-methylguanidines as Prospective PET Radioligands for the Open Channel of the N-Methyl-D-aspartate (NMDA) Receptor: Synthesis a...

por Naumiec, Gregory R., Jenko, Kimberley J., Zoghbi, Sami S., Innis, Robert B., Cai, Lisheng, Pike, Victor W.
Publicado en J Med Chem (2015)

Translocator Protein Ligands Based on N-Methyl-(quinolin-4-yl)oxypropanamides with Properties Suitable for PET Radioligand Development

por Brouwer, Chad, Jenko, Kimberly J., Zoghbi, Sami S., Morse, Cheryl L., Innis, Robert B., Pike, Victor W.
Publicado en Eur J Med Chem (2016)

Quantification of Translocator Protein (18 kDa) in the Human Brain with PET and a Novel Radioligand, (18)F-PBR06

por Fujimura, Yota, Zoghbi, Sami S., Simèon, Fabrice G., Taku, Andrew, Pike, Victor W., Innis, Robert B., Fujita, Masahiro
Publicado 2009

On Quantitative Relationships Between Drug-Like Compound Lipophilicity and Plasma Free Fraction in Monkey and Human

por ZOGHBI, SAMI S., ANDERSON, KACEY B., JENKO, KIMBERLY J., LUCKENBAUGH, DAVID A., INNIS, ROBERT B., PIKE, VICTOR W.
Publicado 2011

Synthesis and Evaluation in Monkey of [(18)F]4-Fluoro-N-methyl-N-(4-(6- (methylamino)pyrimidin-4-yl)thiazol-2-yl)benzamide ([(18)F]FIMX), a Promising Radioligand for PET Imaging of...

por Xu, Rong, Zanotti-Fregonara, Paolo, Zoghbi, Sami S., Gladding, Robert L., Woock, Alicia, Innis, Robert B., Pike, Victor W
Publicado 2013

Improved models for plasma radiometabolite correction and their impact on kinetic quantification in PET studies

por Tonietto, Matteo, Veronese, Mattia, Rizzo, Gaia, Zanotti-Fregonara, Paolo, Lohith, Talakad G, Fujita, Masahiro, Zoghbi, Sami S, Bertoldo, Alessandra
Publicado en J Cereb Blood Flow Metab (2015)

Development of a non-radiometric method for measuring the arterial input function of a (11)C-labeled PET radiotracer

por Shetty, H. Umesha, Zoghbi, Sami S., Morse, Cheryl L., Kowalski, Aneta, Hirvonen, Jussi, Innis, Robert B., Pike, Victor W.
Publicado en Sci Rep (2020)

Stroke incidentally identified using improved positron emission tomography for microglial activation

por Kreisl, William C., Mbeo, Gilbert, Fujita, Masahiro, Zoghbi, Sami S., Pike, Victor W., Innis, Robert B., McArthur, Justin C.
Publicado 2009

Effects of Ketoconazole on the Biodistribution and Metabolism of [(11)C]Loperamide and [(11)C]N-Desmethyl-loperamide in Wild-type and P-gp Knockout Mice

por Seneca, Nicholas, Zoghbi, Sami S., Shetty, H. Umesha, Tuan, Edward, Kannan, Pavitra, Taku, Andrew, Innis, Robert B., Pike, Victor W.
Publicado 2010

Comparison of (18)F- and (11)C-labeled aryloxyanilide analogs to measure translocator protein in human brain using positron emission tomography

por Dickstein, Leah P., Zoghbi, Sami S., Fujimura, Yota, Imaizumi, Masao, Zhang, Yi, Pike, Victor W., Innis, Robert B., Fujita, Masahiro
Publicado 2010

Quantification of metabotropic glutamate subtype 5 receptors in brain by an equilibrium method using (18)F-SP203

por Kimura, Yasuyuki, Siméon, Fabrice G., Zoghbi, Sami S., Zhang, Yi, Hatazawa, Jun, Pike, Victor W., Innis, Robert B., Fujita, Masahiro
Publicado 2011

Application of Calibrated Image Derived Input Function to a Clinical Protocol

por Zanotti-Fregonara, Paolo, Lyoo, Chul Hyoung, Bar-Hen, Avner, Liow, Jeih-San, Zoghbi, Sami S, Fujita, Masahiro, Innis, Robert B.
Publicado 2014

PET Measurement of the In Vivo Affinity of (11)C-(R)-Rolipram and the Density of Its Target, Phosphodiesterase-4, in the Brains of Conscious and Anesthetized Rats

por Itoh, Tetsuji, Abe, Kohji, Zoghbi, Sami S., Inoue, Osamu, Hong, Jinsoo, Imaizumi, Masao, Pike, Victor W., Innis, Robert B., Fujita, Masahiro
Publicado 2009

[(11)C]Rhodamine-123: synthesis and biodistribution in rodents

por Bao, Xiaofeng, Lu, Shuiyu, Liow, Jeih-San, Morse, Cheryl L., Anderson, Kacey, Zoghbi, Sami S., Innis, Robert B., Pike, Victor W.
Publicado 2012

Image-derived input function in PET brain studies: blood-based methods are resistant to motion artifacts

por Zanotti-Fregonara, Paolo, Liow, Jeih-San, Comtat, Claude, Zoghbi, Sami S., Zhang, Yi, Pike, Victor W., Fujita, Masahiro, Innis, Robert B.
Publicado 2012