Translocator Protein Ligands Based on N-Methyl-(quinolin-4-yl)oxypropanamides with Properties Suitable for PET Radioligand Development

Bằng Brouwer, Chad, Jenko, Kimberly J., Zoghbi, Sami S., Morse, Cheryl L., Innis, Robert B., Pike, Victor W.
Xuất bản năm Eur J Med Chem (2016)

Is metabotropic glutamate receptor 5 upregulated in prefrontal cortex in fragile X syndrome?

Bằng Lohith, Talakad G, Osterweil, Emily K, Fujita, Masahiro, Jenko, Kimberly J, Bear, Mark F, Innis, Robert B
Được phát hành 2013

On Quantitative Relationships Between Drug-Like Compound Lipophilicity and Plasma Free Fraction in Monkey and Human

Bằng ZOGHBI, SAMI S., ANDERSON, KACEY B., JENKO, KIMBERLY J., LUCKENBAUGH, DAVID A., INNIS, ROBERT B., PIKE, VICTOR W.
Được phát hành 2011

3-Substituted 1,5-Diaryl-1H-1,2,4-triazoles as Prospective PET Radioligands for Imaging Brain COX-1 in Monkey. Part 1: Synthesis and Pharmacology

Bằng Singh, Prachi, Shrestha, Stal, Cortes-Salva, Michelle Y., Jenko, Kimberly J., Zoghbi, Sami S., Morse, Cheryl L., Innis, Robert B., Pike, Victor W.
Xuất bản năm ACS Chem Neurosci (2018)

Radiosynthesis and evaluation of an (18)F-labeled positron emission tomography (PET) radioligand for brain histamine subtype-3 receptors based on a nonimidazole 2-aminoethylbenzofu...

Bằng Bao, Xiaofeng, Lu, Shuiyu, Liow, Jeih-San, Zoghbi, Sami S., Jenko, Kimberly J., Clark, David T., Gladding, Robert L., Innis, Robert B., Pike, Victor W.
Được phát hành 2012

Neuroinflammation in frontotemporal lobar degeneration revealed by (11)C‐PBR28 PET

Bằng Kim, Min-Jeong, McGwier, Meghan, Jenko, Kimberly J., Snow, Joseph, Morse, Cheryl, Zoghbi, Sami S., Pike, Victor W., Innis, Robert B., Kreisl, William C.
Xuất bản năm Ann Clin Transl Neurol (2019)

Binding of a tritiated inverse agonist to cannabinoid CB(1) receptors is increased in patients with schizophrenia

Bằng Jenko, Kimberly J., Hirvonen, Jussi, Henter, Ioline D., Anderson, Kacey B., Zoghbi, Sami S., Hyde, Thomas M., Deep-Soboslay, Amy, Innis, Robert B., Kleinman, Joel E.
Được phát hành 2012

In vitro and in vivo evaluation of (11)C-SD5024, a novel PET radioligand for human brain imaging of cannabinoid CB(1) receptors

Bằng Tsujikawa, Tetsuya, Zoghbi, Sami S., Hong, Jinsoo, Donohue, Sean R., Jenko, Kimberly J., Gladding, Robert L., Halldin, Christer, Pike, Victor W., Innis, Robert B., Fujita, Masahiro
Được phát hành 2013

[carbonyl-(11)C]4-Fluoro-N-methyl-N-(4-(6-(methylamino)pyrimidin-4-yl)thiazol-2-yl)benzamide ([(11)C]FIMX) is an effective radioligand for PET imaging of metabotropic glutamate rec...

Bằng Hong, Jinsoo, Lu, Shuiyu, Xu, Rong, Liow, Jeih-San, Woock, Alicia E., Jenko, Kimberly J., Gladding, Robert L., Zoghbi, Sami S., Innis, Robert B., Pike, Victor W.
Xuất bản năm Nucl Med Biol (2015)

2-(4-Methylsulfonylphenyl)pyrimidines as Prospective Radioligands for Imaging Cyclooxygenase-2 with PET—Synthesis, Triage, and Radiolabeling

Bằng Cortes-Salva, Michelle Y., Shrestha, Stal, Singh, Prachi, Morse, Cheryl L., Jenko, Kimberly J., Montero Santamaria, Jose A., Zoghbi, Sami S., Innis, Robert B., Pike, Victor W.
Xuất bản năm Molecules (2018)

Distinct patterns of increased translocator protein in posterior cortical atrophy and amnestic Alzheimer’s disease

Bằng Kreisl, William C., Lyoo, Chul Hyoung, Liow, Jeih-San, Snow, Joseph, Page, Emily, Jenko, Kimberly J., Morse, Cheryl L., Zoghbi, Sami S., Pike, Victor W., Turner, R. Scott, Innis, Robert B.
Xuất bản năm Neurobiol Aging (2016)

Synthesis and Evaluation of Translocator 18 kDa Protein (TSPO) Positron Emission Tomography (PET) Radioligands with Low Binding Sensitivity to Human Single Nucleotide Polymorphism...

Bằng Zanotti-Fregonara, Paolo, Zhang, Yi, Jenko, Kimberly J., Gladding, Robert L., Zoghbi, Sami S., Fujita, Masahiro, Sbardella, Gianluca, Castellano, Sabrina, Taliani, Sabrina, Martini, Claudia, Innis, Robert B., Da Settimo, Federico, Pike, Victor W.
Được phát hành 2014

(11)C-PBR28 binding to translocator protein increases with progression of Alzheimer’s disease

Bằng Kreisl, William C., Lyoo, Chul Hyoung, Liow, Jeih-San, Wei, Monica, Snow, Joseph, Page, Emily, Jenko, Kimberly J., Morse, Cheryl L., Zoghbi, Sami S., Pike, Victor W., Turner, R. Scott, Innis, Robert B.
Xuất bản năm Neurobiol Aging (2016)

A genetic polymorphism for translocator protein 18 kDa affects both in vitro and in vivo radioligand binding in human brain to this putative biomarker of neuroinflammation

Bằng Kreisl, William C, Jenko, Kimberly J, Hines, Christina S, Hyoung Lyoo, Chul, Corona, Winston, Morse, Cheryl L, Zoghbi, Sami S, Hyde, Thomas, Kleinman, Joel E, Pike, Victor W, McMahon, Francis J, Innis, Robert B
Được phát hành 2013

Comparison of [(11)C]-(R)-PK 11195 and [(11)C]PBR28, Two Radioligands for Translocator Protein (18 kDa) in Human and Monkey: Implications for Positron Emission Tomographic Imaging...

Bằng Kreisl, William C., Fujita, Masahiro, Fujimura, Yota, Kimura, Nobuyo, Jenko, Kimberly J., Kannan, Pavitra, Hong, Jinsoo, Morse, Cheryl L., Zoghbi, Sami S., Gladding, Robert L., Jacobson, Steven, Oh, Unsong, Pike, Victor W., Innis, Robert B.
Được phát hành 2009

In vivo radioligand binding to translocator protein correlates with severity of Alzheimer’s disease

Bằng Kreisl, William C., Lyoo, Chul Hyoung, McGwier, Meghan, Snow, Joseph, Jenko, Kimberly J., Kimura, Nobuyo, Corona, Winston, Morse, Cheryl L., Zoghbi, Sami S., Pike, Victor W., McMahon, Francis J., Turner, R. Scott, Innis, Robert B.
Được phát hành 2013

3-Substituted 1,5-Diaryl-1H-1,2,4-triazoles as Prospective PET Radioligands for Imaging Brain COX-1 in Monkey. Part 2: Selection and Evaluation of [(11)C]PS13 for Quantitative Imag...

Bằng Shrestha, Stal, Singh, Prachi, Cortes-Salva, Michelle Y., Jenko, Kimberly J., Ikawa, Masamichi, Kim, Min-Jeong, Kobayashi, Masato, Morse, Cheryl L., Gladding, Robert L., Liow, Jeih-San, Zoghbi, Sami S., Fujita, Masahiro, Innis, Robert B., Pike, Victor W.
Xuất bản năm ACS Chem Neurosci (2018)

Neuroinflammation in Temporal Lobe Epilepsy Measured Using Positron Emission Tomographic Imaging of Translocator Protein

Bằng Gershen, Leah P., Zanotti-Fregonara, Paolo, Dustin, Irene H., Liow, Jeih-San, Hirvonen, Jussi, Kreisl, William C., Jenko, Kimberly J., Inati, Sara K., Fujita, Masahiro, Morse, Cheryl L., Brouwer, Chad, Hong, Jinsoo S., Pike, Victor W., Zoghbi, Sami S., Innis, Robert B., Theodore, William H.
Xuất bản năm JAMA Neurol (2015)