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In vitro and in vivo evaluation of (11)C-SD5024, a novel PET radioligand for human brain imaging of cannabinoid CB(1) receptors

We recently developed a novel cannabinoid subtype-1 (CB(1)) receptor radioligand (11)C-SD5024 for brain imaging. This study aimed to evaluate (11)C-SD5024 both in vitro and in vivo and compare it with the other CB(1) receptor ligands previously used in humans, i.e., (11)C-MePPEP, (11)C-OMAR, (18)F-M...

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Autors principals: Tsujikawa, Tetsuya, Zoghbi, Sami S., Hong, Jinsoo, Donohue, Sean R., Jenko, Kimberly J., Gladding, Robert L., Halldin, Christer, Pike, Victor W., Innis, Robert B., Fujita, Masahiro
Format: Artigo
Idioma:Inglês
Publicat: 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3849221/
https://ncbi.nlm.nih.gov/pubmed/24076222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroimage.2013.09.043
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