3-Substituted 1,5-Diaryl-1H-1,2,4-triazoles as Prospective PET Radioligands for Imaging Brain COX-1 in Monkey. Part 2: Selection and Evaluation of [(11)C]PS13 for Quantitative Imaging

In our preceding paper (Part 1), we identified three 1,5-bis-diaryl-1,2,4-triazole-based compounds that merited evaluation as potential positron emission tomography (PET) radioligands for selectively imaging cyclooxygenase-1 (COX-1) in monkey and human brain, namely, 1,5-bis(4-methoxyphenyl)-3-(alko...

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Опубликовано в: :ACS Chem Neurosci
Главные авторы: Shrestha, Stal, Singh, Prachi, Cortes-Salva, Michelle Y., Jenko, Kimberly J., Ikawa, Masamichi, Kim, Min-Jeong, Kobayashi, Masato, Morse, Cheryl L., Gladding, Robert L., Liow, Jeih-San, Zoghbi, Sami S., Fujita, Masahiro, Innis, Robert B., Pike, Victor W.
Формат: Artigo
Язык:Inglês
Опубликовано: 2018
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6371780/
https://ncbi.nlm.nih.gov/pubmed/29792035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschemneuro.8b00103
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