(11)C-CUMI-101, a PET Radioligand, Behaves as a Serotonin 1A Receptor Antagonist and Also Binds to α(1) Adrenoceptors in Brain

The PET radioligand (11)C-CUMI-101 was previously suggested as a putative agonist radioligand for the serotonin 1A (5-hydroxytryptamine 1A [5-HT(1A)]) receptor in recombinant cells expressing human 5-HT(1A) receptor. However, a recent study showed that CUMI-101 behaved as a potent 5-HT(1A) receptor...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Gepubliceerd in:J Nucl Med
Hoofdauteurs: Shrestha, Stal Saurav, Liow, Jeih-San, Lu, Shuiyu, Jenko, Kimberly, Gladding, Robert L., Svenningsson, Per, Morse, Cheryl L., Zoghbi, Sami S., Pike, Victor W., Innis, Robert B.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2014
Onderwerpen:
Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4247002/
https://ncbi.nlm.nih.gov/pubmed/24385311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2967/jnumed.113.125831
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items