Human Biodistribution and Dosimetry of (11)C-CUMI-101, an Agonist Radioligand for Serotonin-1A Receptors in Brain

As a reported agonist,(11)C-CUMI-101 is believed to selectively bind the G-protein-coupled state of the serotonin-1A (5-HT(1A)) receptor, thereby providing a measure of the active subset of all 5-HT(1A) receptors in brain. Although (11)C-CUMI-101 has been successfully used to quantify 5-HT(1A) recep...

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Bibliographische Detailangaben
Hauptverfasser: Hines, Christina S., Liow, Jeih-San, Zanotti-Fregonara, Paolo, Hirvonen, Jussi, Morse, Cheryl, Pike, Victor W., Innis, Robert B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2011
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3181260/
https://ncbi.nlm.nih.gov/pubmed/21980419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0025309
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