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(11)C-CUMI-101, a PET Radioligand, Behaves as a Serotonin 1A Receptor Antagonist and Also Binds to α(1) Adrenoceptors in Brain
The PET radioligand (11)C-CUMI-101 was previously suggested as a putative agonist radioligand for the serotonin 1A (5-hydroxytryptamine 1A [5-HT(1A)]) receptor in recombinant cells expressing human 5-HT(1A) receptor. However, a recent study showed that CUMI-101 behaved as a potent 5-HT(1A) receptor...
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| Publicat a: | J Nucl Med |
|---|---|
| Autors principals: | , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4247002/ https://ncbi.nlm.nih.gov/pubmed/24385311 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2967/jnumed.113.125831 |
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