Evaluation of Two Potent and Selective PET Radioligands to Image COX-1 and COX-2 in Rhesus Monkeys

This study assessed whether the newly developed PET radioligands (11)C-PS13 and (11)C-MC1 could image constitutive levels of cyclooxygenase (COX)-1 and COX-2, respectively, in rhesus monkeys. Methods: After intravenous injection of either radioligand, 24 whole-body PET scans were performed. To measu...

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Bibliografische gegevens
Gepubliceerd in:J Nucl Med
Hoofdauteurs: Kim, Min-Jeong, Shrestha, Stal S., Cortes, Michelle, Singh, Prachi, Morse, Cheryl, Liow, Jeih-San, Gladding, Robert L., Brouwer, Chad, Henry, Katharine, Gallagher, Evan, Tye, George L., Zoghbi, Sami S., Fujita, Masahiro, Pike, Victor W., Innis, Robert B.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Society of Nuclear Medicine 2018
Onderwerpen:
Infection/Inflammation
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6278897/
https://ncbi.nlm.nih.gov/pubmed/29959215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2967/jnumed.118.211144
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