Synthesis, Structure-affinity Relationships and Radiolabeling of Selective High-affinity 5-HT(4) Receptor Ligands as Prospective Imaging Probes for PET

Por Xu, Rong, Hong, Jinsoo, Morse, Cheryl L., Pike, Victor W.
Publicado em 2010

Evaluation of [(11)C]S14506 and [(18)F]S14506 in rat and monkey as agonist PET radioligands for brain 5-HT(1A) receptors

Por Lu, Shuiyu, Liow, Jeih-San, Zoghbi, Sami S., Hong, Jinsoo, Innis, Robert B., Pike, Victor W.
Publicado em 2010

Effects of cAMP-Dependent Protein Kinase Activator and Inhibitor on In Vivo Rolipram Binding to Phosphodiesterase 4 in Conscious Rats

Por ITOH, TETSUJI, ABE, KOHJI, HONG, JINSOO, INOUE, OSAMU, PIKE, VICTOR W., INNIS, ROBERT B., FUJITA, MASAHIRO
Publicado em 2010

IN VIVO BINDING OF PROTOPORPHYRIN IX TO RAT TRANSLOCATOR PROTEIN IMAGED WITH POSITRON EMISSION TOMOGRAPHY

Por Ozaki, Harushige, Zoghbi, Sami S., Hong, Jinsoo, Verma, Ajay, Pike, Victor W., Innis, Robert B., Fujita, Masahiro
Publicado em 2010

[carbonyl-(11)C]Benzyl acetate: automated radiosynthesis via Pd-mediated [(11)C]carbon monoxide chemistry and PET measurement of brain uptake in monkey

Por Lu, Shuiyu, Hong, Jinsoo, Itoh, Tetsuji, Fujita, Masahiro, Inoue, Osamu, Innis, Robert B., Pike, Victor W.
Publicado em 2010

Syntheses of (11)C- and (18)F-labeled carboxylic esters within a hydrodynamically-driven micro-reactor

Por Lu, Shui-Yu, Watts, Paul, Chin, Frederick T., Hong, Jinsoo, Musachio, John L., Briard, Emmanuelle, Pike, Victor W.
Publicado em 2004

PET Measurement of the In Vivo Affinity of (11)C-(R)-Rolipram and the Density of Its Target, Phosphodiesterase-4, in the Brains of Conscious and Anesthetized Rats

Por Itoh, Tetsuji, Abe, Kohji, Zoghbi, Sami S., Inoue, Osamu, Hong, Jinsoo, Imaizumi, Masao, Pike, Victor W., Innis, Robert B., Fujita, Masahiro
Publicado em 2009

Kinetic Analysis in Healthy Humans of a Novel Positron Emission Tomography Radioligand to Image the Peripheral Benzodiazepine Receptor, a Potential Biomarker for Inflammation

Por Fujita, Masahiro, Imaizumi, Masao, Zoghbi, Sami S., Fujimura, Yota, Farris, Amanda G., Suhara, Tetsuya, Hong, Jinsoo, Pike, Victor W., Innis, Robert B.
Publicado em 2007

Brain and Whole-body Imaging in Nonhuman Primates of [(11)C]PBR28, a Promising PET Radioligand for Peripheral Benzodiazepine Receptors

Por Imaizumi, Masao, Briard, Emmanuelle, Zoghbi, Sami S., Gourley, Jonathan P., Hong, Jinsoo, Fujimura, Yota, Pike, Victor W., Innis, Robert B., Fujita, Masahiro
Publicado em 2007

PET Reveals Inflammation around Calcified Taenia solium Granulomas with Perilesional Edema

Por Fujita, Masahiro, Mahanty, Siddhartha, Zoghbi, Sami S., Ferraris Araneta, Maria Desiree, Hong, Jinsoo, Pike, Victor W., Innis, Robert B., Nash, Theodore E.
Publicado em 2013

Synthesis and characterization in monkey of [(11)C]SP203 as a radioligand for imaging brain metabotropic glutamate 5 receptors

Por Siméon, Fabrice G., Liow, Jeih-San, Zhang, Yi, Hong, Jinsoo, Gladding, Robert L., Zoghbi, Sami S., Innis, Robert B., Pike, Victor W.
Publicado no Eur J Nucl Med Mol Imaging (2012)

Dopamine β-hydroxylase-deficient mice have normal densities of D(2) dopamine receptors in the high affinity state based on in vivo PET imaging and in vitro radioligand binding

Por Skinbjerg, Mette, Seneca, Nicholas, Liow, Jeih-San, Hong, Jinsoo, Weinshenker, David, Pike, Victor W., Halldin, Christer, Sibley, David R., Innis, Robert B.
Publicado em 2010

Occupancy of Dopamine D(2/3) Receptors in Rat Brain by Endogenous Dopamine Measured With the Agonist Positron Emission Tomography Radioligand [(11)C]MNPA

Por SENECA, NICHOLAS, ZOGHBI, SAMI S., SKINBJERG, METTE, LIOW, JEIH-SAN, HONG, JINSOO, SIBLEY, DAVID R., PIKE, VICTOR W., HALLDIN, CHRISTER, INNIS, ROBERT B.
Publicado em 2008

Synthesis and Evaluation of [N-methyl-(11)C]N-Desmethyl-loperamide as a New and Improved PET Radiotracer for Imaging P-gp Function

Por Lazarova, Neva, Zoghbi, Sami S., Hong, Jinsoo, Seneca, Nicholas, Tuan, Ed, Gladding, Robert L., Liow, Jeih-San, Taku, Andrew, Innis, Robert B., Pike, Victor W.
Publicado em 2008

In vitro and in vivo evaluation of (11)C-SD5024, a novel PET radioligand for human brain imaging of cannabinoid CB(1) receptors

Por Tsujikawa, Tetsuya, Zoghbi, Sami S., Hong, Jinsoo, Donohue, Sean R., Jenko, Kimberly J., Gladding, Robert L., Halldin, Christer, Pike, Victor W., Innis, Robert B., Fujita, Masahiro
Publicado em 2013

D(2) dopamine receptor internalization prolongs the decrease of radioligand binding after amphetamine: A PET study in a receptor internalization-deficient mouse model

Por Skinbjerg, Mette, Liow, Jeih-San, Seneca, Nicholas, Hong, Jinsoo, Lu, Shuiyu, Thorsell, Annika, Heilig, Markus, Pike, Victor W., Halldin, Christer, Sibley, David R., Innis, Robert B.
Publicado em 2010

[carbonyl-(11)C]4-Fluoro-N-methyl-N-(4-(6-(methylamino)pyrimidin-4-yl)thiazol-2-yl)benzamide ([(11)C]FIMX) is an effective radioligand for PET imaging of metabotropic glutamate rec...

Por Hong, Jinsoo, Lu, Shuiyu, Xu, Rong, Liow, Jeih-San, Woock, Alicia E., Jenko, Kimberly J., Gladding, Robert L., Zoghbi, Sami S., Innis, Robert B., Pike, Victor W.
Publicado no Nucl Med Biol (2015)

The PET Radioligand (18)F-FIMX Images and Quantifies Metabotropic Glutamate Receptor 1 in Proportion to the Regional Density of Its Gene Transcript in Human Brain

Por Zanotti-Fregonara, Paolo, Xu, Rong, Zoghbi, Sami S., Liow, Jeih-San, Fujita, Masahiro, Veronese, Mattia, Gladding, Robert L., Rallis-Frutos, Denise, Hong, Jinsoo, Pike, Victor W., Innis, Robert B.
Publicado no J Nucl Med (2015)

cAMP Signaling in Brain is Decreased in Unmedicated Depressed Patients and Increased by Treatment with a Selective Serotonin Reuptake Inhibitor

Por Fujita, Masahiro, Richards, Erica M., Niciu, Mark J., Ionescu, Dawn F., Zoghbi, Sami S., Hong, Jinsoo, Telu, Sanjay, Hines, Christina S., Pike, Victor W., Zarate, Carlos A., Innis, Robert B.
Publicado no Mol Psychiatry (2016)

Kinetic Brain Analysis and Whole-Body Imaging in Monkey of [(11)C]MNPA: A Dopamine Agonist Radioligand

Por SENECA, NICHOLAS, SKINBJERG, METTE, ZOGHBI, SAMI S., LIOW, JEIH-SAN, GLADDING, ROBERT L., HONG, JINSOO, KANNAN, PAVITRA, TUAN, EDWARD, SIBLEY, DAVID R., HALLDIN, CHRISTER, PIKE, VICTOR W., INNIS, ROBERT B.
Publicado em 2008