D(2) dopamine receptor internalization prolongs the decrease of radioligand binding after amphetamine: A PET study in a receptor internalization-deficient mouse model

Dopamine released by amphetamine decreases the in vivo binding of PET radioligands to the dopamine D(2) receptor. Although concentrations of extracellular dopamine largely return to baseline within one to two hours after amphetamine treatment, radioligand binding remains decreased for several hours....

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Bibliografiske detaljer
Main Authors: Skinbjerg, Mette, Liow, Jeih-San, Seneca, Nicholas, Hong, Jinsoo, Lu, Shuiyu, Thorsell, Annika, Heilig, Markus, Pike, Victor W., Halldin, Christer, Sibley, David R., Innis, Robert B.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2838946/
https://ncbi.nlm.nih.gov/pubmed/20097293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroimage.2010.01.055
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