Kinetic Brain Analysis and Whole-Body Imaging in Monkey of [(11)C]MNPA: A Dopamine Agonist Radioligand

With a view to future extension of the use of the agonist radioligand [(11)C]MNPA ([O-methyl-(11)C]2-methoxy-N-propylnorapomorphine) from animals to humans, we performed two positron emission tomography (PET) studies in monkeys. First, we assessed the ability to quantify the brain uptake of [(11)C]M...

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Autori principali: SENECA, NICHOLAS, SKINBJERG, METTE, ZOGHBI, SAMI S., LIOW, JEIH-SAN, GLADDING, ROBERT L., HONG, JINSOO, KANNAN, PAVITRA, TUAN, EDWARD, SIBLEY, DAVID R., HALLDIN, CHRISTER, PIKE, VICTOR W., INNIS, ROBERT B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2786063/
https://ncbi.nlm.nih.gov/pubmed/18566975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/syn.20544
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