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Dopamine β-hydroxylase-deficient mice have normal densities of D(2) dopamine receptors in the high affinity state based on in vivo PET imaging and in vitro radioligand binding
In vitro, D(2) dopamine receptors can exist in low and high affinity states for agonists, and increases of D(2) receptors in high affinity state have been proposed to underlie dopamine receptor supersensitivity in vivo. Deletion of the gene for dopamine β-hydroxylase (DBH) causes mice to become hype...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2894264/ https://ncbi.nlm.nih.gov/pubmed/20336622 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/syn.20781 |
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