The PET Radioligand (18)F-FIMX Images and Quantifies Metabotropic Glutamate Receptor 1 in Proportion to the Regional Density of Its Gene Transcript in Human Brain

A recent study from our laboratory found that (18)F-FIMX is an excellent PET radioligand for quantifying metabotropic glutamate receptor 1 (mGluR1) in monkey brain. This study evaluated the ability of (18)F-FIMX to quantify mGluR1 in humans. A second goal was to use the relative density of mGluR1 ge...

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Detalhes bibliográficos
Publicado no:J Nucl Med
Main Authors: Zanotti-Fregonara, Paolo, Xu, Rong, Zoghbi, Sami S., Liow, Jeih-San, Fujita, Masahiro, Veronese, Mattia, Gladding, Robert L., Rallis-Frutos, Denise, Hong, Jinsoo, Pike, Victor W., Innis, Robert B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4983720/
https://ncbi.nlm.nih.gov/pubmed/26514176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2967/jnumed.115.162461
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