Synthesis and Evaluation in Monkey of [(18)F]4-Fluoro-N-methyl-N-(4-(6- (methylamino)pyrimidin-4-yl)thiazol-2-yl)benzamide ([(18)F]FIMX), a Promising Radioligand for PET Imaging of Brain Metabotropic Glutamate Receptor 1 (mGluR1)

We sought to develop a PET radioligand that would be useful for imaging human brain metabotropic subtype 1 receptors (mGluR1) in neuropsychiatric disorders and in drug development. 4-Fluoro-N-methyl-N-(4-(6-(methylamino)pyrimidin-4-yl)thiazol-2-yl)benzamide (FIMX, 11) was identified as having favora...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Xu, Rong, Zanotti-Fregonara, Paolo, Zoghbi, Sami S., Gladding, Robert L., Woock, Alicia, Innis, Robert B., Pike, Victor W
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3866693/
https://ncbi.nlm.nih.gov/pubmed/24147864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm4012017
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados