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Synthesis, Structure-affinity Relationships and Radiolabeling of Selective High-affinity 5-HT(4) Receptor Ligands as Prospective Imaging Probes for PET

In a search for high-affinity receptor ligands that might serve for development as radioligands for the imaging of brain 5-HT(4) receptors in vivo with positron emission tomography (PET), structural modifications were made to the high-affinity 5-HT(4) antagonist, (1-butylpiperidin-4-yl)methyl 8-amin...

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Detalhes bibliográficos
Main Authors: Xu, Rong, Hong, Jinsoo, Morse, Cheryl L., Pike, Victor W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2951497/
https://ncbi.nlm.nih.gov/pubmed/20812727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm100668r
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