تحميل...
Synthesis and Evaluation of [N-methyl-(11)C]N-Desmethyl-loperamide as a New and Improved PET Radiotracer for Imaging P-gp Function
[(11)C]Loperamide has been proposed for imaging P-glycoprotein (P-gp) function with positron emission tomography (PET), but its metabolism to [N-methyl-(11)C]N-desmethyl-loperamide ([(11)C]dLop; [(11)C]3) precludes quantification. We considered that [(11)C]3 might itself be a superior radiotracer fo...
محفوظ في:
| المؤلفون الرئيسيون: | , , , , , , , , , |
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| التنسيق: | Artigo |
| اللغة: | Inglês |
| منشور في: |
2008
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| الموضوعات: | |
| الوصول للمادة أونلاين: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2646255/ https://ncbi.nlm.nih.gov/pubmed/18783208 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm800510m |
| الوسوم: |
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