Human Brain Imaging and Radiation Dosimetry of (11)C-N-Desmethyl-Loperamide, a PET Radiotracer to Measure the Function of P-Glycoprotein

P-glycoprotein (P-gp) is a membrane-bound efflux pump that limits the distribution of drugs to several organs of the body. At the blood–brain barrier, P-gp blocks the entry of both loperamide and its metabolite, N-desmethyl-loperamide (N-dLop), and thereby prevents central opiate effects. Animal stu...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Glavni autori: Seneca, Nicholas, Zoghbi, Sami S., Liow, Jeih-San, Kreisl, William, Herscovitch, Peter, Jenko, Kimberly, Gladding, Robert L., Taku, Andrew, Pike, Victor W., Innis, Robert B.
Format: Artigo
Jezik:Inglês
Izdano: 2009
Teme:
Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2792991/
https://ncbi.nlm.nih.gov/pubmed/19372478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2967/jnumed.108.058453
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!

Similar Items