cAMP Signaling in Brain is Decreased in Unmedicated Depressed Patients and Increased by Treatment with a Selective Serotonin Reuptake Inhibitor

Basic studies exploring the importance of the cyclic adenosine monophosphate (cAMP) cascade in major depressive disorder (MDD) have noted that the cAMP cascade is downregulated in MDD and upregulated by antidepressant treatment. We investigated cAMP cascade activity by using (11)C-(R)-rolipram to im...

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Publicado no:Mol Psychiatry
Main Authors: Fujita, Masahiro, Richards, Erica M., Niciu, Mark J., Ionescu, Dawn F., Zoghbi, Sami S., Hong, Jinsoo, Telu, Sanjay, Hines, Christina S., Pike, Victor W., Zarate, Carlos A., Innis, Robert B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5388600/
https://ncbi.nlm.nih.gov/pubmed/27725657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mp.2016.171
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