Anxiety and depression with neurogenesis defects in exchange protein directly activated by cAMP 2-deficient mice are ameliorated by a selective serotonin reuptake inhibitor, Prozac

Intracellular cAMP and serotonin are important modulators of anxiety and depression. Fluoxetine, a selective serotonin reuptake inhibitor (SSRI) also known as Prozac, is widely used against depression, potentially by activating cAMP response element-binding protein (CREB) and increasing brain-derive...

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Bibliographische Detailangaben
Veröffentlicht in:Transl Psychiatry
Hauptverfasser: Zhou, L, Ma, S L, Yeung, P K K, Wong, Y H, Tsim, K W K, So, K F, Lam, L C W, Chung, S K
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2016
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5048194/
https://ncbi.nlm.nih.gov/pubmed/27598965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/tp.2016.129
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