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cAMP Signaling in Brain is Decreased in Unmedicated Depressed Patients and Increased by Treatment with a Selective Serotonin Reuptake Inhibitor

Basic studies exploring the importance of the cyclic adenosine monophosphate (cAMP) cascade in major depressive disorder (MDD) have noted that the cAMP cascade is downregulated in MDD and upregulated by antidepressant treatment. We investigated cAMP cascade activity by using (11)C-(R)-rolipram to im...

詳細記述

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書誌詳細
出版年:Mol Psychiatry
主要な著者: Fujita, Masahiro, Richards, Erica M., Niciu, Mark J., Ionescu, Dawn F., Zoghbi, Sami S., Hong, Jinsoo, Telu, Sanjay, Hines, Christina S., Pike, Victor W., Zarate, Carlos A., Innis, Robert B.
フォーマット: Artigo
言語:Inglês
出版事項: 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5388600/
https://ncbi.nlm.nih.gov/pubmed/27725657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mp.2016.171
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