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Comparison of (18)F- and (11)C-labeled aryloxyanilide analogs to measure translocator protein in human brain using positron emission tomography
PURPOSE: Translocator protein (TSPO) is a promising biomarker for neuroinflammation. We developed two new PET ligands, (18)F-PBR06 and (11)C-PBR28, to image TSPOs. Although our prior studies suggest that either of the two ligands could be used to quantify TSPOs in human brain, the studies were done...
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Auteurs principaux: | , , , , , , , |
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Format: | Artigo |
Langue: | Inglês |
Publié: |
2010
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Sujets: | |
Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3159870/ https://ncbi.nlm.nih.gov/pubmed/21085954 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00259-010-1622-y |
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