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Comparison of (18)F- and (11)C-labeled aryloxyanilide analogs to measure translocator protein in human brain using positron emission tomography

PURPOSE: Translocator protein (TSPO) is a promising biomarker for neuroinflammation. We developed two new PET ligands, (18)F-PBR06 and (11)C-PBR28, to image TSPOs. Although our prior studies suggest that either of the two ligands could be used to quantify TSPOs in human brain, the studies were done...

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Detalhes bibliográficos
Main Authors: Dickstein, Leah P., Zoghbi, Sami S., Fujimura, Yota, Imaizumi, Masao, Zhang, Yi, Pike, Victor W., Innis, Robert B., Fujita, Masahiro
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3159870/
https://ncbi.nlm.nih.gov/pubmed/21085954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00259-010-1622-y
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