Quantification of Translocator Protein (18 kDa) in the Human Brain with PET and a Novel Radioligand, (18)F-PBR06

Translocator protein (TSPO) (18 kDa), formerly called the peripheral benzodiazepine receptor, is upregulated on activated microglia and macrophages and is, thus, a biomarker of inflammation. We previously reported that an (11)C-labeled aryloxyanilide (half-life, 20 min) was able to quantify TSPOs in...

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Detalhes bibliográficos
Main Authors: Fujimura, Yota, Zoghbi, Sami S., Simèon, Fabrice G., Taku, Andrew, Pike, Victor W., Innis, Robert B., Fujita, Masahiro
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2786064/
https://ncbi.nlm.nih.gov/pubmed/19525468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2967/jnumed.108.060186
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