Activation of transient receptor potential ankyrin 1 induces CGRP release from spinal cord synaptosomes

Bằng Quallo, Talisia, Gentry, Clive, Bevan, Stuart, Broad, Lisa M., Mogg, Adrian J.
Xuất bản năm Pharmacol Res Perspect (2015)

TRPV3 in Drug Development

Bằng Broad, Lisa M., Mogg, Adrian J., Eberle, Elizabeth, Tolley, Marcia, Li, Dominic L., Knopp, Kelly L.
Xuất bản năm Pharmaceuticals (Basel) (2016)

Monocytes expressing CX3CR1 orchestrate the development of vincristine-induced pain

Bằng Old, Elizabeth A., Nadkarni, Suchita, Grist, John, Gentry, Clive, Bevan, Stuart, Kim, Ki-Wook, Mogg, Adrian J., Perretti, Mauro, Malcangio, Marzia
Được phát hành 2014

Pharmacological profiling of the TRPV3 channel in recombinant and native assays

Bằng Grubisha, Olivera, Mogg, Adrian J, Sorge, Jessica L, Ball, Laura-Jayne, Sanger, Helen, Ruble, Cara L A, Folly, Elizabeth A, Ursu, Daniel, Broad, Lisa M
Được phát hành 2014

Activation of Muscarinic M1 Acetylcholine Receptors Induces Long-Term Potentiation in the Hippocampus

Bằng Dennis, Siobhan H., Pasqui, Francesca, Colvin, Ellen M., Sanger, Helen, Mogg, Adrian J., Felder, Christian C., Broad, Lisa M., Fitzjohn, Steve M., Isaac, John T.R., Mellor, Jack R.
Xuất bản năm Cereb Cortex (2016)

Identification and pharmacological profile of SPP1, a potent, functionally selective and brain penetrant agonist at muscarinic M(1) receptors

Bằng Broad, Lisa M, Sanger, Helen E, Mogg, Adrian J, Colvin, Ellen M, Zwart, Ruud, Evans, David A, Pasqui, Francesca, Sher, Emanuele, Wishart, Graham N, Barth, Vanessa N, Felder, Christian C, Goldsmith, Paul J
Xuất bản năm Br J Pharmacol (2018)

Bitopic Binding Mode of an M(1) Muscarinic Acetylcholine Receptor Agonist Associated with Adverse Clinical Trial Outcomes

Bằng Bradley, Sophie J., Molloy, Colin, Bundgaard, Christoffer, Mogg, Adrian J., Thompson, Karen J., Dwomoh, Louis, Sanger, Helen E., Crabtree, Michael D., Brooke, Simon M., Sexton, Patrick M., Felder, Christian C., Christopoulos, Arthur, Broad, Lisa M., Tobin, Andrew B., Langmead, Christopher J.
Xuất bản năm Mol Pharmacol (2018)

In Vitro Pharmacological Characterization and In Vivo Validation of LSN3172176 a Novel M1 Selective Muscarinic Receptor Agonist Tracer Molecule for Positron Emission Tomography

Bằng Mogg, Adrian J., Eessalu, Thomas, Johnson, Megan, Wright, Rebecca, Sanger, Helen E., Xiao, Hongling, Crabtree, Michael G., Smith, Alex, Colvin, Ellen M., Schober, Douglas, Gehlert, Donald, Jesudason, Cynthia, Goldsmith, Paul J., Johnson, Michael P., Felder, Christian C., Barth, Vanessa N., Broad, Lisa M.
Xuất bản năm J Pharmacol Exp Ther (2018)

M1 muscarinic allosteric modulators slow prion neurodegeneration and restore memory loss

Bằng Bradley, Sophie J., Bourgognon, Julie-Myrtille, Sanger, Helen E., Verity, Nicholas, Mogg, Adrian J., White, David J., Butcher, Adrian J., Moreno, Julie A., Molloy, Colin, Macedo-Hatch, Timothy, Edwards, Jennifer M., Wess, Jurgen, Pawlak, Robert, Read, David J., Sexton, Patrick M., Broad, Lisa M., Steinert, Joern R., Mallucci, Giovanna R., Christopoulos, Arthur, Felder, Christian C., Tobin, Andrew B.
Xuất bản năm J Clin Invest (2016)

Biased M1-muscarinic-receptor-mutant mice inform the design of next-generation drugs

Bằng Bradley, Sophie J., Molloy, Colin, Valuskova, Paulina, Dwomoh, Louis, Scarpa, Miriam, Rossi, Mario, Finlayson, Lisa, Svensson, Kjell A., Chernet, Eyassu, Barth, Vanessa N., Gherbi, Karolina, Sykes, David A., Wilson, Caroline A., Mistry, Rajendra, Sexton, Patrick M., Christopoulos, Arthur, Mogg, Adrian J., Rosethorne, Elizabeth M., Sakata, Shuzo, Challiss, R. A. John, Broad, Lisa M., Tobin, Andrew B.
Xuất bản năm Nat Chem Biol (2020)