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Brain and Whole-Body Imaging of Nociceptin/Orphanin FQ Peptide Receptor in Humans Using the PET Ligand (11)C-NOP-1A

Nociceptin/orphanin FQ peptide (NOP) receptor is a new class of opioid receptor that may play a pathophysiologic role in anxiety and drug abuse and is a potential therapeutic target in these disorders. We previously developed a high-affinity PET ligand, (11)C-NOP-1A, which yielded promising results...

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Detalhes bibliográficos
Main Authors: Lohith, Talakad G., Zoghbi, Sami S., Morse, Cheryl L., Araneta, Maria F., Barth, Vanessa N., Goebl, Nancy A., Tauscher, Johannes T., Pike, Victor W., Innis, Robert B., Fujita, Masahiro
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3835399/
https://ncbi.nlm.nih.gov/pubmed/22312136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2967/jnumed.111.097162
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