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The Nociceptin/Orphanin FQ Receptor (NOP) as a Target for Drug Abuse Medications
Several studies show that the nociceptin receptor NOP plays a role in the regulation of reward and motivation pathways related to substance abuse. Administration of the NOP’s natural peptide ligand, Nociceptin/Orphanin FQ (N/OFQ) or synthetic agonist Ro 64-6198 has been shown to block rewarding effe...
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| Main Author: | |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2011
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3899399/ https://ncbi.nlm.nih.gov/pubmed/21050175 |
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