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The Nociceptin/Orphanin FQ Receptor (NOP) as a Target for Drug Abuse Medications

Several studies show that the nociceptin receptor NOP plays a role in the regulation of reward and motivation pathways related to substance abuse. Administration of the NOP’s natural peptide ligand, Nociceptin/Orphanin FQ (N/OFQ) or synthetic agonist Ro 64-6198 has been shown to block rewarding effe...

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Bibliographic Details
Main Author: Zaveri, Nurulain T.
Format: Artigo
Language:Inglês
Published: 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3899399/
https://ncbi.nlm.nih.gov/pubmed/21050175
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