Nociceptin/Orphanin FQ Receptor Activation Attenuates Antinociception Induced by Mixed Nociceptin/Orphanin FQ/μ-Opioid Receptor Agonists

Activation of brain nociceptin/orphanin FQ (NOP) receptors leads to attenuation of μ-opioid receptor (MOP receptor)-mediated antinociception. Buprenorphine, a high-affinity partial MOP receptor agonist also binds to NOP receptors with 80 nM affinity. The buprenorphine-induced inverted U-shaped dose-...

Full beskrivning

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Khroyan, Taline V., Polgar, Willma E., Jiang, Faming, Zaveri, Nurulain T., Toll, Lawrence
Materialtyp: Artigo
Språk:Inglês
Publicerad: The American Society for Pharmacology and Experimental Therapeutics 2009
Ämnen:
Behavioral Pharmacology
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2784721/
https://ncbi.nlm.nih.gov/pubmed/19713488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.109.156711
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk