Structure-activity relationships and docking studies of synthetic 2-arylindole derivatives determined with aromatase and quinone reductase 1

Por Prior, Allan M., Yu, Xufen, Park, Eun-Jung, Kondratyuk, Tamara P., Lin, Yan, Pezzuto, John M., Sun, Dianqing
Publicado no Bioorg Med Chem Lett (2017)

Evaluation of the cyclopentane-1,2-dione as a potential bio-isostere of the carboxylic acid functional group

Por Ballatore, Carlo, Gay, Bryant, Huang, Longchuan, Robinson, Katie Herbst, James, Michael, Trojanowski, John Q., Lee, Virginia M.Y., Brunden, Kurt R., Smith, Amos B.
Publicado em 2014

Potent, Long-Acting Cyclopentane-1,3-Dione Thromboxane (A(2))-Receptor Antagonists

Por Wang, Xiaozhao, Liu, Li, Huang, Longchuan, Herbst-Robinson, Katie, Cornec, Anne-Sophie, James, Michael J., Sugiyama, Shimpei, Bassetto, Marcella, Brancale, Andrea, Trojanowski, John Q., Lee, Virginia M.-Y., Smith, Amos B., Brunden, Kurt R., Ballatore, Carlo
Publicado em 2014

The effects of phenolic glycosides from Betula platyphylla var. japonica on adipocyte differentiation and mature adipocyte metabolism

Por Huh, Joo Young, Lee, Seulah, Ma, Eun-Bi, Eom, Hee Jeong, Baek, Jiwon, Ko, Yoon-Joo, Kim, Ki Hyun
Publicado no J Enzyme Inhib Med Chem (2018)

Design, Synthesis, and Biological Evaluation of Indenoisoquinoline Rexinoids with Chemopreventive Potential

Por Conda-Sheridan, Martin, Park, Eun-Jung, Beck, Daniel E., Narasimha Reddy, P. V., Nguyen, Trung X., Hu, Bingjie, Chen, Lian, White, Jerry J., van Breemen, Richard B., Pezzuto, John M., Cushman, Mark
Publicado em 2013

Synthesis and structure–activity relationship studies of tyrosine-based antagonists at the human P2X(7) receptor

Por Lee, Ga Eun, Joshi, Bhalchandra V., Chen, Wangzhong, Jeong, Lak Shin, Moon, Hyung Ryong, Jacobson, Kenneth A., Kim, Yong-Chul
Publicado em 2007

Design, synthesis, and biological evaluation of callophycin A and analogues as potential chemopreventive and anticancer agents

Por Shen, Li, Park, Eun-Jung, Kondratyuk, Tamara P., Guendisch, Daniela, Marler, Laura, Pezzuto, John M., Wright, Anthony D., Sun, Dianqing
Publicado em 2011

Aminothienopyridazine inhibitors of tau aggregation: Evaluation of structure–activity relationship leads to selection of candidates with desirable in vivo properties

Por Ballatore, Carlo, Crowe, Alex, Piscitelli, Francesco, James, Michael, Lou, Kevin, Rossidivito, Gabrielle, Yao, Yuemang, Trojanowski, John Q., Lee, Virginia M.-Y., Brunden, Kurt R., Smith, Amos B.
Publicado no Bioorg Med Chem (2012)

Cyclopentane-1,3-dione: A Novel Isostere for the Carboxylic Acid Functional Group. Application to the Design of Potent Thromboxane (A2)-Receptor Antagonists

Por Ballatore, Carlo, Soper, James, Piscitelli, Francesco, James, Michael, Huang, Longchuan, Atasoylu, Onur, Huryn, Donna M., Trojanowski, John Q., Lee, Virginia M.-Y., Brunden, Kurt R., Smith, Amos B.
Publicado em 2011

Design and Synthesis of a Novel and Selective Kappa Opioid Receptor (KOR) Antagonist (BTRX-335140)

Por Guerrero, Miguel, Urbano, Mariangela, Kim, Eun-Kyong, Gamo, Ana M., Riley, Sean, Abgaryan, Lusine, Leaf, Nora, Van Orden, Lori Jean, Brown, Steven J., Xie, Jennifer Y., Porreca, Frank, Cameron, Michael D., Rosen, Hugh, Roberts, Edward
Publicado no J Med Chem (2019)

Design, synthesis and evaluation of photoactivatable derivatives of microtubule (MT)-active [1,2,4]triazolo[1,5-a]pyrimidines

Por Oukoloff, Killian, Kovalevich, Jane, Cornec, Anne-Sophie, Yao, Yuemang, Owyang, Zachary A., James, Michael, Trojanowski, John Q., Lee, Virginia M.-Y., Smith, Amos B., Brunden, Kurt R., Ballatore, Carlo
Publicado no Bioorg Med Chem Lett (2018)

Antileishmanial Activity of a Series of N(2),N(4)-Disubstituted Quinazoline-2,4-diamines

Por Van Horn, Kurt S., Zhu, Xiaohua, Pandharkar, Trupti, Yang, Sihyung, Vesely, Brian, Vanaerschot, Manu, Dujardin, Jean-Claude, Rijal, Suman, Kyle, Dennis E., Wang, Michael Zhuo, Werbovetz, Karl A., Manetsch, Roman
Publicado em 2014

OGA inhibition by GlcNAc-selenazoline

Por Kim, Eun Ju, Love, Dona C., Darout, Etzer, Abdo, Mohannad, Rempel, Brian, Withers, Stephen G., Rablen, Paul R., Hanover, John A., Knapp, Spencer
Publicado em 2010

Synthesis and evaluation of quinoxaline derivatives as potential influenza NS1A protein inhibitors

Por You, Lei, Cho, Eun Jeong, Leavitt, John, Ma, Li-Chung, Montelione, Gaetano T., Anslyn, Eric V., Krug, Robert M., Ellington, Andrew, Robertus, Jon D.
Publicado em 2011

Selective Synthesis and Biological Evaluation of Sulfate-Conjugated Resveratrol Metabolites

Por Hoshino, Juma, Park, Eun-Jung, Kondratyuk, Tamara P., Marler, Laura, Pezzuto, John M., van Breemen, Richard B., Mo, Shunyan, Li, Yongchao, Cushman, Mark
Publicado em 2010

Potent and Selective Inhibitors of Human Reticulocyte 12/15-Lipoxygenase as Anti-Stroke Therapies

Por Rai, Ganesha, Joshi, Netra, Jung, Joo Eun, Liu, Yu, Schultz, Lena, Yasgar, Adam, Perry, Steve, Diaz, Giovanni, Zhang, Qiangli, Kenyon, Victor, Jadhav, Ajit, Simeonov, Anton, Lo, Eng H., van Leyen, Klaus, Maloney, David J., Holman, Theodore R.
Publicado em 2014

Structural Basis of Wee Kinases Functionality and Inactivation by Diverse Small Molecule Inhibitors

Por Zhu, Jin-Yi, Cuellar, Rebecca A., Berndt, Norbert, Lee, Hee Eun, Olesen, Sanne H., Martin, Mathew P., Jensen, Jeffrey T., Georg, Gunda I., Schönbrunn, Ernst
Publicado no J Med Chem (2017)

Synthesis, characterization and antineoplastic activity of bis-aziridinyl dimeric naphthoquinone - a novel class of compounds with potent activity against acute myeloid leukemia ce...

Por Carter-Cooper, Brandon A., Fletcher, Steven, Ferraris, Dana, Choi, Eun Yong, Kronfli, Dahlia, Dash, Smaraki, Truong, Phuc, Sausville, Edward A., Lapidus, Rena G., Emadi, Ashkan
Publicado no Bioorg Med Chem Lett (2016)

Potential Chemopreventive Agents Based on the Structure of the Lead Compound 2-Bromo-1-hydroxyphenazine, Isolated from Streptomyces sp., Strain CNS284

Por Conda-Sheridan, Martin, Marler, Laura, Park, Eun-Jung, Kondratyuk, Tamara P., Jermihov, Katherine, Mesecar, Andrew D., Pezzuto, John M., Asolkar, Ratnakar N., Fenical, William, Cushman, Mark
Publicado em 2010

Identification, Synthesis, and Biological Evaluation of the Metabolites of 3-Amino-6-(3'-aminopropyl)-5H-indeno[1,2-c]isoquinoline-5,11-(6H)dione (AM6-36), a Promising Rexinoid Lea...

Por Chen, Lian, Conda-Sheridan, Martin, Narasimha Reddy, P. V., Morrell, Andrew, Park, Eun-Jung, Kondratyuk, Tamara P., Pezzuto, John M., van Breemen, Richard B., Cushman, Mark
Publicado em 2012