The β-galactosidase-catalysed hydrolyses of β-d-galactopyranosyl pyridinium salts. Rate-limiting generation of an enzyme-bound galactopyranosyl cation in a process dependent only o...

Por Sinnott, Michael L., Withers, Stephen G.
Publicado em 1974

Glycosynthase-catalysed formation of modified polysaccharide microstructures .

Por Watts, Andrew G, Withers, Stephen G
Publicado em 2004

Periplasmic de-acylase helps bacteria don their biofilm coat

Por Kwan, David H., Withers, Stephen G.
Publicado em 2014

Proteolytic Cleavage Driven by Glycosylation

Por Kötzler, Miriam P., Withers, Stephen G.
Publicado no J Biol Chem (2016)

Subsite structure of the endo-type chitin deacetylase from a deuteromycete, Colletotrichum lindemuthianum: an investigation using steady-state kinetic analysis and MS.

Por Hekmat, Omid, Tokuyasu, Ken, Withers, Stephen G
Publicado em 2003

Paenibacillus sp. TS12 glucosylceramidase: kinetic studies of a novel sub-family of family 3 glycosidases and identification of the catalytic residues.

Por Paal, Krisztina, Ito, Makoto, Withers, Stephen G
Publicado em 2004

N-Acetylglucosaminidases from CAZy Family GH3 Are Really Glycoside Phosphorylases, Thereby Explaining Their Use of Histidine as an Acid/Base Catalyst in Place of Glutamic Acid

Por Macdonald, Spencer S., Blaukopf, Markus, Withers, Stephen G.
Publicado no J Biol Chem (2015)

Mechanistic Investigations of Unsaturated Glucuronyl Hydrolase from Clostridium perfringens

Por Jongkees, Seino A. K., Yoo, Hayoung, Withers, Stephen G.
Publicado em 2014

Interaction of the lacZ β-galactosidase of Escherichia coli with some β-d-galactopyranoside competitive inhibitors

Por Loeffler, R. S. Thomas, Sinnott, Michael L., Sykes, Brian D., Withers, Stephen G.
Publicado em 1979

HIGH-THROUGHPUT SCREENING FOR NOVEL HUMAN LYSOSOMAL BETA-N-ACETYL HEXOSAMINIDASE INHIBITORS ACTING AS PHARMACOLOGICAL CHAPERONES

Por Tropak, Michael B., Blanchard, Jan, Withers, Stephen G., Brown, Eric, Mahuran, Don
Publicado em 2007

Characterization of the Glu and Asp Residues in the Active Site of Human β-Hexosaminidase B

Por Hou, Yongmin, Vocadlo, David J., Leung, Amy, Withers, Stephen G., Mahuran, Don
Publicado em 2001

α-Galacturonidase(s): a new class of Family 4 glycoside hydrolases with strict specificity and a unique CHEV active site motif

Por Thompson, John, Pikis, Andreas, Rich, Jamie, Hall, Barry G., Withers, Stephen G.
Publicado em 2013

Pharmacological Enhancement of β-Hexosaminidase Activity in Fibroblasts from Adult Tay-Sachs and Sandhoff Patients

Por Tropak, Michael B., Reid, Stephen P., Guiral, Marianne, Withers, Stephen G., Mahuran, Don
Publicado em 2004

Mechanistic investigation of the endo-α-N-acetylgalactosaminidase from Streptococcus pneumoniae R6

Por Willis, Lisa M., Zhang, Ran, Reid, Anne, Withers, Stephen G., Wakarchuk, Warren W.
Publicado em 2009

The role of the oligosaccharide binding cleft of rice BGlu1 in hydrolysis of cellooligosaccharides and in their synthesis by rice BGlu1 glycosynthase

Por Pengthaisong, Salila, Withers, Stephen G, Kuaprasert, Buabarn, Svasti, Jisnuson, Ketudat Cairns, James R
Publicado em 2012

A New Sialidase Mechanism: BACTERIOPHAGE K1F ENDO-SIALIDASE IS AN INVERTING GLYCOSIDASE

Por Morley, Thomas J., Willis, Lisa M., Whitfield, Chris, Wakarchuk, Warren W., Withers, Stephen G.
Publicado em 2009

A general and efficient strategy for generating the stable enzymes

Por Zhang, Xiao-Fei, Yang, Guang-Yu, Zhang, Yong, Xie, Yuan, Withers, Stephen G., Feng, Yan
Publicado no Sci Rep (2016)

Thioglycoligase-Based Assembly of Thiodisaccharides: Screening as β-Galactosidase Inhibitors

Por Kim, Young-Wan, Chen, Hong-Ming, Kim, Jin Hyo, Müllegger, Johannes, Mahuran, Don, Withers, Stephen G.
Publicado em 2007

The structure of the Mycobacterium smegmatis trehalose synthase reveals an unusual active site configuration and acarbose-binding mode(†)

Por Caner, Sami, Nguyen, Nham, Aguda, Adeleke, Zhang, Ran, Pan, Yuan T, Withers, Stephen G, Brayer, Gary D
Publicado em 2013

Structural and Kinetic Characterizations of the Polysialic Acid O-Acetyltransferase OatWY from Neisseria meningitidis

Por Lee, Ho Jun, Rakić, Bojana, Gilbert, Michel, Wakarchuk, Warren W., Withers, Stephen G., Strynadka, Natalie C. J.
Publicado em 2009