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A New Sialidase Mechanism: BACTERIOPHAGE K1F ENDO-SIALIDASE IS AN INVERTING GLYCOSIDASE

Bacteriophages specific for Escherichia coli K1 express a tailspike protein that degrades the polysialic acid coat of E. coli K1 that is essential for bacteriophage infection. This enzyme is specific for polysialic acid and is a member of a family of endo-sialidases. This family is unusual because a...

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Main Authors: Morley, Thomas J., Willis, Lisa M., Whitfield, Chris, Wakarchuk, Warren W., Withers, Stephen G.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2719380/
https://ncbi.nlm.nih.gov/pubmed/19411257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.003970
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