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Mechanistic investigation of the endo-α-N-acetylgalactosaminidase from Streptococcus pneumoniae R6

The large (1767 amino acid) endo-α-N-acetylgalactosaminidase from Streptococcus pneumoniae (SpGH101) specifically removes an O-linked disaccharide Gal-β-1,3-GalNAc-α from glycoproteins. While the enzyme from natural sources has been used as a reagent for many years, very few mechanistic studies have...

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Detalhes bibliográficos
Main Authors: Willis, Lisa M., Zhang, Ran, Reid, Anne, Withers, Stephen G., Wakarchuk, Warren W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2953539/
https://ncbi.nlm.nih.gov/pubmed/19788271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi9013825
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