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Remarkable Transglycosylation Activity of Glycosynthase Mutants of Endo-D, an Endo-β-N-acetylglucosaminidase from Streptococcus pneumoniae

Endo-β-N-acetylglucosaminidase from Streptococcus pneumoniae (Endo-D) is an endoglycosidase capable of hydrolyzing the Fc N-glycan of intact IgG antibodies after sequential removal of the sialic acid, galactose, and internal GlcNAc residues in the N-glycan. Endo-D also possesses transglycosylation a...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Fan, Shu-Quan, Huang, Wei, Wang, Lai-Xi
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3322811/
https://ncbi.nlm.nih.gov/pubmed/22318728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.340497
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