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The structure of the Mycobacterium smegmatis trehalose synthase reveals an unusual active site configuration and acarbose-binding mode(†)

Trehalose synthase (TreS) catalyzes the reversible conversion of maltose into trehalose in mycobacteria as one of three biosynthetic pathways to this nonreducing disaccharide. Given the importance of trehalose to survival of mycobacteria, there has been considerable interest in understanding the enz...

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Detalles Bibliográficos
Main Authors: Caner, Sami, Nguyen, Nham, Aguda, Adeleke, Zhang, Ran, Pan, Yuan T, Withers, Stephen G, Brayer, Gary D
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3724413/
https://ncbi.nlm.nih.gov/pubmed/23735230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/glycob/cwt044
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