Homology Modelling of Human E1 Ubiquitin Activating Enzyme

Por Brahemi, Ghali, Burger, Angelika M., Westwell, Andrew D., Brancale, Andrea
Publicado em 2010

The role of substrate specificity and metal binding in defining the activity and structure of an intracellular subtilisin

Por Gamble, Michael, Künze, Georg, Brancale, Andrea, Wilson, Keith S., Jones, D. Dafydd
Publicado em 2012

Base damage, local sequence context and TP53 mutation hotspots: a molecular dynamics study of benzo[a]pyrene induced DNA distortion and mutability

Por Menzies, Georgina E., Reed, Simon H., Brancale, Andrea, Lewis, Paul D.
Publicado no Nucleic Acids Res (2015)

Therapeutically targeting guanylate cyclase‐C: computational modeling of plecanatide, a uroguanylin analog

Por Brancale, Andrea, Shailubhai, Kunwar, Ferla, Salvatore, Ricci, Antonio, Bassetto, Marcella, Jacob, Gary S
Publicado no Pharmacol Res Perspect (2017)

Amyloid-Associated Nucleic Acid Hybridisation

Por Braun, Sebastian, Humphreys, Christine, Fraser, Elizabeth, Brancale, Andrea, Bochtler, Matthias, Dale, Trevor C.
Publicado em 2011

ProTides of BVdU as potential anticancer agents upon efficient intracellular delivery of their activated metabolites

Por Kandil, Sahar, Balzarini, Jan, Rat, Stephanie, Brancale, Andrea, Westwell, Andrew D., McGuigan, Christopher
Publicado no Bioorg Med Chem Lett (2016)

The application of phosphoramidate ProTide technology to acyclovir confers anti-HIV inhibition

Por Derudas, Marco, Carta, Davide, Brancale, Andrea, Vanpouille, Christophe, Lisco, Andrea, Margolis, Leonid, Balzarini, Jan, McGuigan, Christopher
Publicado em 2009

Convergent Synthesis and Biological Evaluation of 2-Amino-4-(3′,4′,5′-trimethoxyphenyl)-5-aryl Thiazoles as Microtubule Targeting Agents

Por Romagnoli, Romeo, Baraldi, Pier Giovanni, Brancale, Andrea, Ricci, Antonio, Hamel, Ernest, Bortolozzi, Roberta, Basso, Giuseppe, Viola, Giampietro
Publicado em 2011

Importance of single molecular determinants in the fidelity of expanded genetic codes

Por Antonczak, Alicja K., Simova, Zuzana, Yonemoto, Isaac T., Bochtler, Matthias, Piasecka, Anna, Czapińska, Honorata, Brancale, Andrea, Tippmann, Eric M.
Publicado em 2011

Exploring the Structural Requirements for Inhibition of the Ubiquitin E3 Ligase Breast Cancer Associated Protein 2 (BCA2) as a Treatment for Breast Cancer

Por Brahemi, Ghali, Kona, Fathima R., Fiasella, Annalisa, Buac, Daniela, Soukupová, Jitka, Brancale, Andrea, Burger, Angelika M., Westwell, Andrew D.
Publicado em 2010

Characterization of the Mode of Action of a Potent Dengue Virus Capsid Inhibitor

Por Scaturro, Pietro, Trist, Iuni Margaret Laura, Paul, David, Kumar, Anil, Acosta, Eliana G., Byrd, Chelsea M., Jordan, Robert, Brancale, Andrea, Bartenschlager, Ralf
Publicado em 2014

Impairment of cocaine-mediated behaviours in mice by clinically relevant Ras-ERK inhibitors

Por Papale, Alessandro, Morella, Ilaria Maria, Indrigo, Marzia Tina, Bernardi, Rick Eugene, Marrone, Livia, Marchisella, Francesca, Brancale, Andrea, Spanagel, Rainer, Brambilla, Riccardo, Fasano, Stefania
Publicado no eLife (2016)

Synthesis of novel antimitotic agents based on 2-amino-3-aroyl-5-(hetero)arylethynyl thiophene derivatives

Por Romagnoli, Romeo, Baraldi, Pier Giovanni, Cruz-Lopez, Olga, Tolomeo, Manlio, Di Cristina, Antonietta, Pipitone, Rosaria Maria, Grimaudo, Stefania, Balzarini, Jan, Brancale, Andrea, Hamel, Ernest
Publicado em 2010

Synthesis and Antitumor Activity of 1,5-Disubstituted 1,2,4-Triazoles as Cis-Restricted Combretastatin Analogues

Por Romagnoli, Romeo, Baraldi, Pier Giovanni, Cruz-Lopez, Olga, Lopez Cara, Carlota, Carrion, Maria Dora, Brancale, Andrea, Hamel, Ernest, Chen, Longchuan, Bortolozzi, Roberta, Basso, Giuseppe, Viola, Giampietro
Publicado em 2010

Substituted 2-(3′,4′,5′-trimethoxybenzoyl)-benzo[b]thiophene derivatives as potent tubulin polymerization inhibitors

Por Romagnoli, Romeo, Baraldi, Pier Giovanni, Carrion, Maria Dora, Cruz-Lopez, Olga, Tolomeo, Manlio, Grimaudo, Stefania, Di Cristina, Antonietta, Pipitone, Maria Rosaria, Balzarini, Jan, Brancale, Andrea, Hamel, Ernest
Publicado em 2010

Synthesis and Biological Evaluation of 2- (Alkoxycarbonyl)-3-Anilinobenzo[b]thiophenes and Thieno[2,3-b]pyridines as New Potent Anticancer Agents

Por Romagnoli, Romeo, Baraldi, Pier Giovanni, Salvador, Maria Kimatrai, Preti, Delia, Tabrizi, Mojgan Aghazadeh, Bassetto, Marcella, Brancale, Andrea, Hamel, Ernest, Castagliuolo, Ignazio, Bortolozzi, Roberta, Basso, Giuseppe, Viola, Giampietro
Publicado em 2013

Synthesis and biological evaluation of 2-substituted-4-(3′,4′,5′-trimethoxyphenyl)-5-aryl thiazoles as anticancer agents

Por Romagnoli, Romeo, Baraldi, Pier Giovanni, Salvador, Maria Kimatrai, Camacho, M. Encarnacion, Preti, Delia, Tabrizi, Mojgan Aghazadeh, Bassetto, Marcella, Brancale, Andrea, Hamel, Ernest, Bortolozzi, Roberta, Basso, Giuseppe, Viola, Giampietro
Publicado em 2012

Synthesis, Antimitotic and Antivascular Activity of 1-(3′,4′,5′-Trimethoxybenzoyl)-3-arylamino-5-amino-1,2,4-triazoles

Por Romagnoli, Romeo, Baraldi, Pier Giovanni, Salvador, Maria Kimatrai, Prencipe, Filippo, Bertolasi, Valerio, Cancellieri, Michela, Brancale, Andrea, Hamel, Ernest, Castagliuolo, Ignazio, Consolaro, Francesca, Porcú, Elena, Basso, Giuseppe, Viola, Giampietro
Publicado em 2014

2-Arylamino-4-Amino-5-Aroylthiazoles. “One-Pot” Synthesis and Biological Evaluation of a New Class of Inhibitors of Tubulin Polymerization

Por Romagnoli, Romeo, Baraldi, Pier Giovanni, Carrion, Maria Dora, Cruz-Lopez, Olga, Cara, Carlota Lopez, Basso, Giuseppe, Viola, Giampietro, Khedr, Mohammed, Balzarini, Jan, Mahboobi, Siavosh, Sellmer, Andreas, Brancale, Andrea, Hamel, Ernest
Publicado em 2009

One-pot synthesis and biological evaluation of 2-pyrrolidinyl-4-amino-5-(3′,4′,5′-trimethoxybenzoyl)thiazole: A unique, highly active antimicrotubule agent

Por Romagnoli, Romeo, Baraldi, Pier Giovanni, Cara, Carlota Lopez, Salvador, Maria Kimatrai, Bortolozzi, Roberta, Basso, Giuseppe, Viola, Giampietro, Balzarini, Jan, Brancale, Andrea, Fu, Xian-Hua, Li, Jun, Zhang, Su-Zhan, Hamel, Ernest
Publicado em 2011