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Therapeutically targeting guanylate cyclase‐C: computational modeling of plecanatide, a uroguanylin analog
Plecanatide is a recently developed guanylate cyclase‐C (GC‐C) agonist and the first uroguanylin analog designed to treat chronic idiopathic constipation (CIC) and irritable bowel syndrome with constipation (IBS‐C). GC‐C receptors are found across the length of the intestines and are thought to play...
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| 出版年: | Pharmacol Res Perspect |
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| 主要な著者: | , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
John Wiley and Sons Inc.
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5368960/ https://ncbi.nlm.nih.gov/pubmed/28357122 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prp2.295 |
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