Synthesis, Antimitotic and Antivascular Activity of 1-(3′,4′,5′-Trimethoxybenzoyl)-3-arylamino-5-amino-1,2,4-triazoles

[Image: see text] A new class of compounds that incorporated the structural motif of the 1-(3′,4′,5′-trimethoxtbenzoyl)-3-arylamino-5-amino-1,2,4-triazole molecular skeleton was synthesized and evaluated for their antiproliferative activity in vitro, interactions with tubulin, and cell cycle effects...

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Detalhes bibliográficos
Main Authors: Romagnoli, Romeo, Baraldi, Pier Giovanni, Salvador, Maria Kimatrai, Prencipe, Filippo, Bertolasi, Valerio, Cancellieri, Michela, Brancale, Andrea, Hamel, Ernest, Castagliuolo, Ignazio, Consolaro, Francesca, Porcú, Elena, Basso, Giuseppe, Viola, Giampietro
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4159078/
https://ncbi.nlm.nih.gov/pubmed/25025853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm5008193
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