Synthesis and fluorosolvatochromism of 3-arylnaphtho[1,2-b]quinolizinium derivatives

door Pithan, Phil M, Decker, David, Sardo, Manlio Sutero, Viola, Giampietro, Ihmels, Heiko
Gepubliceerd in Beilstein J Org Chem (2016)

Ecdysteroid Derivatives that Reverse P-Glycoprotein-Mediated Drug Resistance

door Bortolozzi, Roberta, Luraghi, Andrea, Mattiuzzo, Elena, Sacchetti, Alessandro, Silvani, Alessandra, Viola, Giampietro
Gepubliceerd in J Nat Prod (2020)

FOXM1 is overexpressed in B-acute lymphoblastic leukemia (B-ALL) and its inhibition sensitizes B-ALL cells to chemotherapeutic drugs

door CONSOLARO, FRANCESCA, BASSO, GIUSEPPE, GHAEM-MAGAMI, SADAF, LAM, ERIC W.-F., VIOLA, GIAMPIETRO
Gepubliceerd in Int J Oncol (2015)

Synthesis and in vitro Evaluation of 3H-Pyrrolo[3,2-f]-quinolin-9-one Derivatives That Show Potent and Selective Anti-leukemic Activity

door Ferlin, Maria Grazia, Bortolozzi, Roberta, Brun, Paola, Castagliuolo, Ignazio, Hamel, Ernest, Basso, Giuseppe, Viola, Giampietro
Gepubliceerd in 2010

Novel 3-Substituted 7-Phenylpyrrolo[3,2-f]quinolin-9(6H)-ones as Single Entities with Multitarget Antiproliferative Activity

door Carta, Davide, Bortolozzi, Roberta, Hamel, Ernest, Basso, Giuseppe, Moro, Stefano, Viola, Giampietro, Ferlin, Maria Grazia
Gepubliceerd in J Med Chem (2015)

Synthesis and biological evaluation of 2-(3′,4′,5′-trimethoxybenzoyl)-3-aryl/arylaminobenzo[b]thiophene derivatives as a novel class of antiproliferative agents

door Romagnoli, Romeo, Baraldi, Pier Giovanni, Cara, Carlota Lopez, Hamel, Ernest, Basso, Giuseppe, Bortolozzi, Roberta, Viola, Giampietro
Gepubliceerd in 2010

A novel copper(I) complex induces ER-stress-mediated apoptosis and sensitizes B-acute lymphoblastic leukemia cells to chemotherapeutic agents

door Bortolozzi, Roberta, Viola, Giampietro, Porcù, Elena, Consolaro, Francesca, Marzano, Cristina, Pellei, Maura, Gandin, Valentina, Basso, Giuseppe
Gepubliceerd in 2014

Convergent Synthesis and Biological Evaluation of 2-Amino-4-(3′,4′,5′-trimethoxyphenyl)-5-aryl Thiazoles as Microtubule Targeting Agents

door Romagnoli, Romeo, Baraldi, Pier Giovanni, Brancale, Andrea, Ricci, Antonio, Hamel, Ernest, Bortolozzi, Roberta, Basso, Giuseppe, Viola, Giampietro
Gepubliceerd in 2011

MG-2477, a new tubulin inhibitor, induces autophagy through inhibition of the Akt/mTOR pathway and delayed apoptosis in A549 cells

door Viola, Giampietro, Bortolozzi, Roberta, Hamel, Ernest, Moro, Stefano, Brun, Paola, Castagliuolo, Ignazio, Ferlin, Maria Grazia, Basso, Giuseppe
Gepubliceerd in 2011

The tubulin inhibitor MG-2477 induces autophagy-regulated cell death, ROS accumulation and activation of FOXO3 in neuroblastoma

door Hagenbuchner, Judith, Lungkofler, Lorena, Kiechl-Kohlendorfer, Ursula, Viola, Giampietro, Ferlin, Maria Grazia, Ausserlechner, Michael J., Obexer, Petra
Gepubliceerd in Oncotarget (2017)

Hemiasterlin analogues incorporating an aromatic, and heterocyclic type C-terminus: design, synthesis and biological evaluation

door Lesma, Giordano, Sacchetti, Alessandro, Bai, Rouli, Basso, Giuseppe, Bortolozzi, Roberta, Hamel, Ernest, Silvani, Alessandra, Vaiana, Nadia, Viola, Giampietro
Gepubliceerd in 2014

The Novel Antitubulin Agent TR-764 Strongly Reduces Tumor Vasculature and Inhibits HIF-1α Activation

door Porcù, Elena, Persano, Luca, Ronca, Roberto, Mitola, Stefania, Bortolozzi, Roberta, Romagnoli, Romeo, Oliva, Paola, Basso, Giuseppe, Viola, Giampietro
Gepubliceerd in Sci Rep (2016)

Identification of novel indole derivatives acting as inhibitors of the Keap1–Nrf2 interaction

door Cosimelli, Barbara, Greco, Giovanni, Laneri, Sonia, Novellino, Ettore, Sacchi, Antonia, Amendola, Giorgio, Cosconati, Sandro, Bortolozzi, Roberta, Viola, Giampietro
Gepubliceerd in J Enzyme Inhib Med Chem (2019)

Therapy-resistant acute lymphoblastic leukemia (ALL) cells inactivate FOXO3 to escape apoptosis induction by TRAIL and Noxa

door Ausserlechner, Michael J., Salvador, Christina, Deutschmann, Andrea, Bodner, Martin, Viola, Giampietro, Bortolozzi, Roberta, Basso, Giuseppe, Hagenbuchner, Judith, Obexer, Petra
Gepubliceerd in 2013

Synthesis, biological evaluation and molecular docking studies of trans-indole-3-acrylamide derivatives, a new class of tubulin polymerization inhibitors

door Baytas, Sultan Nacak, Inceler, Nazan, Yılmaz, Akın, Olgac, Abdurrahman, Menevse, Sevda, Banoglu, Erden, Hamel, Ernest, Bortolozzi, Roberta, Viola, Giampietro
Gepubliceerd in 2014

Autophagic flux inhibition enhances cytotoxicity of the receptor tyrosine kinase inhibitor ponatinib

door Corallo, Diana, Pastorino, Fabio, Pantile, Marcella, Mariotto, Elena, Caicci, Federico, Viola, Giampietro, Ponzoni, Mirco, Tonini, Gian Paolo, Aveic, Sanja
Gepubliceerd in J Exp Clin Cancer Res (2020)

Targeting tubulin polymerization by novel 7-aryl-pyrroloquinolinones: Synthesis, biological activity and SARs

door Bortolozzi, Roberta, Mattiuzzo, Elena, Dal Pra, Matteo, Sturlese, Mattia, Moro, Stefano, Hamel, Ernest, Carta, Davide, Viola, Giampietro, Ferlin, Maria Grazia
Gepubliceerd in Eur J Med Chem (2017)

Evaluation of Technical Issues in a Pilot Multicenter Newborn Screening Program for Sickle Cell Disease

door Martella, Maddalena, Viola, Giampietro, Azzena, Silvia, Schiavon, Sara, Biondi, Andrea, Basso, Giuseppe, Corti, Paola, Colombatti, Raffaella, Masera, Nicoletta, Sainati, Laura
Gepubliceerd in Int J Neonatal Screen (2018)

Benzo[b]quinolizinium Derivatives Have a Strong Antimalarial Activity and Inhibit Indoleamine Dioxygenase

door Jortzik, Esther, Zocher, Kathleen, Isernhagen, Antje, Mailu, Boniface M., Rahlfs, Stefan, Viola, Giampietro, Wittlin, Sergio, Hunt, Nicholas H., Ihmels, Heiko, Becker, Katja
Gepubliceerd in Antimicrob Agents Chemother (2015)

Improvement and extension of anti-EGFR targeting in breast cancer therapy by integration with the Avidin-Nucleic-Acid-Nano-Assemblies

door Roncato, Francesco, Rruga, Fatlum, Porcù, Elena, Casarin, Elisabetta, Ronca, Roberto, Maccarinelli, Federica, Realdon, Nicola, Basso, Giuseppe, Alon, Ronen, Viola, Giampietro, Morpurgo, Margherita
Gepubliceerd in Nat Commun (2018)