X-Linked Inhibitor of Apoptosis Protein – A Critical Death Resistance Regulator and Therapeutic Target for Personalized Cancer Therapy

অনুযায়ী Obexer, Petra, Ausserlechner, Michael J.
প্রকাশিত 2014

A novel Mcl1 variant inhibits apoptosis via increased Bim sequestration

অনুযায়ী Hagenbuchner, Judith, Kiechl-Kohlendorfer, Ursula, Obexer, Petra, Ausserlechner, Michael J.
প্রকাশিত 2013

Endothelial cells from cord blood CD133(+)CD34(+) progenitors share phenotypic, functional and gene expression profile similarities with lymphatics

অনুযায়ী Nguyen, Van Anh, Fürhapter, Christina, Obexer, Petra, Stössel, Hella, Romani, Nikolaus, Sepp, Norbert
প্রকাশিত 2009

Synthesis and Characterization of Telmisartan‐Derived Cell Death Modulators to Circumvent Imatinib Resistance in Chronic Myeloid Leukemia

অনুযায়ী Schoepf, Anna M., Salcher, Stefan, Hohn, Verena, Veider, Florina, Obexer, Petra, Gust, Ronald
প্রকাশিত ChemMedChem (2020)

The tubulin inhibitor MG-2477 induces autophagy-regulated cell death, ROS accumulation and activation of FOXO3 in neuroblastoma

অনুযায়ী Hagenbuchner, Judith, Lungkofler, Lorena, Kiechl-Kohlendorfer, Ursula, Viola, Giampietro, Ferlin, Maria Grazia, Ausserlechner, Michael J., Obexer, Petra
প্রকাশিত Oncotarget (2017)

Repression of BIRC5/Survivin by FOXO3/FKHRL1 Sensitizes Human Neuroblastoma Cells to DNA Damage-induced Apoptosis

অনুযায়ী Obexer, Petra, Hagenbuchner, Judith, Unterkircher, Thomas, Sachsenmaier, Nora, Seifarth, Christoph, Böck, Günther, Porto, Verena, Geiger, Kathrin, Ausserlechner, Michael
প্রকাশিত 2009

Evaluation of assays for drug efficacy in a three-dimensional model of the lung

অনুযায়ী Huber, Julia M., Amann, Arno, Koeck, Stefan, Lorenz, Edith, Kelm, Jens M., Obexer, Petra, Zwierzina, Heinz, Gamerith, Gabriele
প্রকাশিত J Cancer Res Clin Oncol (2016)

The Anti-apoptotic Protein BCL2L1/Bcl-xL Is Neutralized by Pro-apoptotic PMAIP1/Noxa in Neuroblastoma, Thereby Determining Bortezomib Sensitivity Independent of Prosurvival MCL1 Ex...

অনুযায়ী Hagenbuchner, Judith, Ausserlechner, Michael J., Porto, Verena, David, Reinhard, Meister, Bernhard, Bodner, Martin, Villunger, Andreas, Geiger, Kathrin, Obexer, Petra
প্রকাশিত 2010

Therapy-resistant acute lymphoblastic leukemia (ALL) cells inactivate FOXO3 to escape apoptosis induction by TRAIL and Noxa

অনুযায়ী Ausserlechner, Michael J., Salvador, Christina, Deutschmann, Andrea, Bodner, Martin, Viola, Giampietro, Bortolozzi, Roberta, Basso, Giuseppe, Hagenbuchner, Judith, Obexer, Petra
প্রকাশিত 2013

p16(INK4A) Sensitizes Human Leukemia Cells to FAS- and Glucocorticoid-induced Apoptosis via Induction of BBC3/Puma and Repression of MCL1 and BCL2

অনুযায়ী Obexer, Petra, Hagenbuchner, Judith, Rupp, Martina, Salvador, Christina, Holzner, Markus, Deutsch, Martin, Porto, Verena, Kofler, Reinhard, Unterkircher, Thomas, Ausserlechner, Michael J.
প্রকাশিত 2009

Repaglinide Silences the FOXO3/Lumican Axis and Represses the Associated Metastatic Potential of Neuronal Cancer Cells

অনুযায়ী Salcher, Stefan, Spoden, Gilles, Huber, Julia M., Golderer, Georg, Lindner, Herbert, Ausserlechner, Michael J., Kiechl-Kohlendorfer, Ursula, Geiger, Kathrin, Obexer, Petra
প্রকাশিত Cells (2019)

Monocyte-mediated T-cell suppression and augmented monocyte tryptophan catabolism after human hematopoietic stem-cell transplantation

অনুযায়ী Hainz, Ursula, Obexer, Petra, Winkler, Christiana, Sedlmayr, Peter, Takikawa, Osamu, Greinix, Hildegard, Lawitschka, Anita, Pütschger, Ulrike, Fuchs, Dietmar, Ladisch, Stephan, Heitger, Andreas
প্রকাশিত 2005

FOXO3/FKHRL1 is activated by 5-aza-2-deoxycytidine and induces silenced caspase-8 in neuroblastoma

অনুযায়ী Geiger, Kathrin, Hagenbuchner, Judith, Rupp, Martina, Fiegl, Heidi, Sergi, Consolato, Meister, Bernhard, Kiechl-Kohlendorfer, Ursula, Müller, Thomas, Ausserlechner, Michael J., Obexer, Petra
প্রকাশিত 2012

Nuclear FOXO3 predicts adverse clinical outcome and promotes tumor angiogenesis in neuroblastoma

অনুযায়ী Hagenbuchner, Judith, Rupp, Martina, Salvador, Christina, Meister, Bernhard, Kiechl-Kohlendorfer, Ursula, Müller, Thomas, Geiger, Kathrin, Sergi, Consolato, Obexer, Petra, Ausserlechner, Michael J.
প্রকাশিত Oncotarget (2016)

C10ORF10/DEPP, a transcriptional target of FOXO3, regulates ROS-sensitivity in human neuroblastoma

অনুযায়ী Salcher, Stefan, Hagenbuchner, Judith, Geiger, Kathrin, Seiter, Maximilian A, Rainer, Johannes, Kofler, Reinhard, Hermann, Martin, Kiechl-Kohlendorfer, Ursula, Ausserlechner, Michael J, Obexer, Petra
প্রকাশিত 2014

Discovery of Sanggenon G as a natural cell-permeable small-molecular weight inhibitor of X-linked inhibitor of apoptosis protein (XIAP)

অনুযায়ী Seiter, Maximilian A., Salcher, Stefan, Rupp, Martina, Hagenbuchner, Judith, Kiechl-Kohlendorfer, Ursula, Mortier, Jérémie, Wolber, Gerhard, Rollinger, Judith M., Obexer, Petra, Ausserlechner, Michael J.
প্রকাশিত 2014

Toll-Like Receptor 9 expression in breast and ovarian cancer is associated with poorly differentiated tumors

অনুযায়ী Berger, Regina, Fiegl, Heidi, Goebel, Georg, Obexer, Petra, Ausserlechner, Michael, Doppler, Wolfgang, Hauser-Kronberger, Cornelia, Reitsamer, Roland, Egle, Daniel, Reimer, Daniel, Müller-Holzner, Elisabeth, Jones, Allison, Widschwendter, Martin
প্রকাশিত 2010

Modulating FOXO3 transcriptional activity by small, DBD-binding molecules

অনুযায়ী Hagenbuchner, Judith, Obsilova, Veronika, Kaserer, Teresa, Kaiser, Nora, Rass, Bettina, Psenakova, Katarina, Docekal, Vojtech, Alblova, Miroslava, Kohoutova, Klara, Schuster, Daniela, Aneichyk, Tatsiana, Vesely, Jan, Obexer, Petra, Obsil, Tomas, Ausserlechner, Michael J
প্রকাশিত eLife (2019)

A drug library screen identifies Carbenoxolone as novel FOXO inhibitor that overcomes FOXO3-mediated chemoprotection in high-stage neuroblastoma

অনুযায়ী Salcher, Stefan, Spoden, Gilles, Hagenbuchner, Judith, Führer, Sebastian, Kaserer, Teresa, Tollinger, Martin, Huber-Cantonati, Petra, Gruber, Thomas, Schuster, Daniela, Gust, Ronald, Zwierzina, Heinz, Müller, Thomas, Kiechl-Kohlendorfer, Ursula, Ausserlechner, Michael J., Obexer, Petra
প্রকাশিত Oncogene (2019)

Abstracts of the 52nd Workshop for Pediatric Research: Frankfurt, Germany. 27-28 October 2016

অনুযায়ী van den Bruck, Rhea, Weil, Patrick P., Ziegenhals, Thomas, Schreiner, Philipp, Juranek, Stefan, Gödde, Daniel, Vogel, Silvia, Schuster, Frauke, Orth, Valerie, Dörner, Johannes, Pembaur, Daniel, Röper, Meike, Störkel, Stefan, Zirngibl, Hubert, Wirth, Stefan, Jenke, Andreas C. W., Postberg, Jan, Boy, Nikolas, Heringer, Jana, Haege, Gisela, Glahn, Esther M., Hoffmann, Georg F., Garbade, Sven F., Burgard, Peter, Kölker, Stefan, Chao, Cho-Ming, Yahya, Faady, Moiseenko, Alena, Shrestha, Amit, Ahmadvand, Negah, Quantius, Jennifer, Wilhelm, Jochen, El-Agha, Elie, Zimmer, Klaus-Peter, Bellusci, Saverio, Staufner, Christian, Kölker, Stefan, Prokisch, Holger, Hoffmann, Georg F., Seeliger, Stephan, Müller, Matthias, Hippe, Andreas, Steinkraus, Henrik, Wauer, Roland, Lachmann, Burkhard, Hofmann, Sigrun R., Hedrich, Christian M., Zierk, Jakob, Arzideh, Farhad, Haeckel, Rainer, Rascher, Wolfgang, Rauh, Manfred, Metzler, Markus, Thieme, Sebastian, Bandoła, Joanna, Richter, Cornelia, Ryser, Martin, Jamal, Arshad, Ashton, Michelle P., von Bonin, Malte, Kuhn, Matthias, Hedrich, Christian M., Bonifacio, Ezio, Berner, Reinhard, Brenner, Sebastian, Hammersen, Johanna, Has, Cristina, Naumann-Bartsch, Nora, Stachel, Daniel, Kiritsi, Dimitra, Söder, Stephan, Tardieu, Mathilde, Metzler, Markus, Bruckner-Tuderman, Leena, Schneider, Holm, Bohne, F., Langer, D., Cencic, R., Eggermann, T., Zechner, U., Pelletier, J., Zepp, F., Enklaar, T., Prawitt, D., Pech, Martin, Weckmann, Markus, Heinsen, Femke-Anouska, Franke, Andre, Happle, Christine, Dittrich, Anna-Maria, Hansen, Gesine, Fuchs, Oliver, von Mutius, Erika, Oliver, Brian G., Kopp, Matthias V., Paret, Claudia, Russo, Alexandra, Theruvath, Johanna, Keller, Bettina, El Malki, Khalifa, Lehmann, Nadine, Wingerter, Arthur, Neu, Marie A., Aslihan, Gerhold-Ay, Wagner, Wolfgang, Sommer, Clemens, Pietsch, Torsten, Seidmann, Larissa, Faber, Jörg, Schreiner, Felix, Ackermann, Merle, Michalik, Michael, Rother, Eva, Bilkei-Gorzo, Andras, Racz, Ildiko, Bindila, Laura, Lutz, Beat, Dötsch, Jörg, Zimmer, Andreas, Woelfle, Joachim, Fischer, Hendrik S., Ullrich, Tim L., Bührer, Christoph, Czernik, Christoph, Schmalisch, Gerd, Stein, Robert, Hofmann, Sigrun R., Hagenbuchner, Judith, Kiechl-Kohlendorfer, Ursula, Obexer, Petra, Ausserlechner, Michael J., Loges, Niki T., Frommer, Adrien Tobias, Wallmeier, Julia, Omran, Heymut, Öner-Sieben, Soner, Gimpfl, Martina, Rozman, Jan, Irmler, Martin, Beckers, Johannes, De Angelis, Martin Hrabe, Roscher, Adelbert, Wolf, Eckhard, Ensenauer, Regina, Nemes, Karolina, Frühwald, Michael, Hasselblatt, Martin, Siebert, Reiner, Kordes, Uwe, Kool, Marcel, Wang, Haicui, Hardy, Holly, Refai, Osama, Barwick, Katy E. S., Zimmerman, Holly H., Weis, Joachim, Baple, Emma L., Crosby, Andrew H., Cirak, Sebahattin, Hellmuth, C., Uhl, O., Standl, M., Heinrich, J., Thiering, E., Koletzko, B., Blümel, Lena, Kerl, Kornelius, Picard, Daniel, Frühwald, Michael C., Liebau, Max C., Reifenberger, Guido, Borkhardt, Arndt, Hasselblatt, Martin, Remke, Marc, Tews, D., Wabitsch, M., Fischer-Posovszky, P., Westhoff, Mike-Andrew, Nonnenmacher, Lisa, Langhans, Julia, Schneele, Lukas, Trenkler, Nancy, Debatin, Klaus-Michael
প্রকাশিত Mol Cell Pediatr (2017)