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FOXO3/FKHRL1 is activated by 5-aza-2-deoxycytidine and induces silenced caspase-8 in neuroblastoma

Forkhead box O (FOXO) transcription factors control diverse cellular functions, such as cell death, metabolism, and longevity. We analyzed FOXO3/FKHRL1 expression and subcellular localization in tumor sections of neuroblastoma patients and observed a correlation between nuclear FOXO3 and high caspas...

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Bibliografiske detaljer
Main Authors: Geiger, Kathrin, Hagenbuchner, Judith, Rupp, Martina, Fiegl, Heidi, Sergi, Consolato, Meister, Bernhard, Kiechl-Kohlendorfer, Ursula, Müller, Thomas, Ausserlechner, Michael J., Obexer, Petra
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Cell Biology 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3364184/
https://ncbi.nlm.nih.gov/pubmed/22493319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E11-06-0535
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