Mitochondria and FOXO3: breath or die

Por Hagenbuchner, Judith, Ausserlechner, Michael J.
Publicado em 2013

Mitochondrial survivin – an Achilles’ heel in cancer chemoresistance

Por Ausserlechner, Michael J., Hagenbuchner, Judith
Publicado no Mol Cell Oncol (2015)

A novel Mcl1 variant inhibits apoptosis via increased Bim sequestration

Por Hagenbuchner, Judith, Kiechl-Kohlendorfer, Ursula, Obexer, Petra, Ausserlechner, Michael J.
Publicado em 2013

Repression of BIRC5/Survivin by FOXO3/FKHRL1 Sensitizes Human Neuroblastoma Cells to DNA Damage-induced Apoptosis

Por Obexer, Petra, Hagenbuchner, Judith, Unterkircher, Thomas, Sachsenmaier, Nora, Seifarth, Christoph, Böck, Günther, Porto, Verena, Geiger, Kathrin, Ausserlechner, Michael
Publicado em 2009

The Anti-apoptotic Protein BCL2L1/Bcl-xL Is Neutralized by Pro-apoptotic PMAIP1/Noxa in Neuroblastoma, Thereby Determining Bortezomib Sensitivity Independent of Prosurvival MCL1 Ex...

Por Hagenbuchner, Judith, Ausserlechner, Michael J., Porto, Verena, David, Reinhard, Meister, Bernhard, Bodner, Martin, Villunger, Andreas, Geiger, Kathrin, Obexer, Petra
Publicado em 2010

Therapy-resistant acute lymphoblastic leukemia (ALL) cells inactivate FOXO3 to escape apoptosis induction by TRAIL and Noxa

Por Ausserlechner, Michael J., Salvador, Christina, Deutschmann, Andrea, Bodner, Martin, Viola, Giampietro, Bortolozzi, Roberta, Basso, Giuseppe, Hagenbuchner, Judith, Obexer, Petra
Publicado em 2013

p16(INK4A) Sensitizes Human Leukemia Cells to FAS- and Glucocorticoid-induced Apoptosis via Induction of BBC3/Puma and Repression of MCL1 and BCL2

Por Obexer, Petra, Hagenbuchner, Judith, Rupp, Martina, Salvador, Christina, Holzner, Markus, Deutsch, Martin, Porto, Verena, Kofler, Reinhard, Unterkircher, Thomas, Ausserlechner, Michael J.
Publicado em 2009

FOXO3/FKHRL1 is activated by 5-aza-2-deoxycytidine and induces silenced caspase-8 in neuroblastoma

Por Geiger, Kathrin, Hagenbuchner, Judith, Rupp, Martina, Fiegl, Heidi, Sergi, Consolato, Meister, Bernhard, Kiechl-Kohlendorfer, Ursula, Müller, Thomas, Ausserlechner, Michael J., Obexer, Petra
Publicado em 2012

Nuclear FOXO3 predicts adverse clinical outcome and promotes tumor angiogenesis in neuroblastoma

Por Hagenbuchner, Judith, Rupp, Martina, Salvador, Christina, Meister, Bernhard, Kiechl-Kohlendorfer, Ursula, Müller, Thomas, Geiger, Kathrin, Sergi, Consolato, Obexer, Petra, Ausserlechner, Michael J.
Publicado no Oncotarget (2016)

C10ORF10/DEPP, a transcriptional target of FOXO3, regulates ROS-sensitivity in human neuroblastoma

Por Salcher, Stefan, Hagenbuchner, Judith, Geiger, Kathrin, Seiter, Maximilian A, Rainer, Johannes, Kofler, Reinhard, Hermann, Martin, Kiechl-Kohlendorfer, Ursula, Ausserlechner, Michael J, Obexer, Petra
Publicado em 2014

Discovery of Sanggenon G as a natural cell-permeable small-molecular weight inhibitor of X-linked inhibitor of apoptosis protein (XIAP)

Por Seiter, Maximilian A., Salcher, Stefan, Rupp, Martina, Hagenbuchner, Judith, Kiechl-Kohlendorfer, Ursula, Mortier, Jérémie, Wolber, Gerhard, Rollinger, Judith M., Obexer, Petra, Ausserlechner, Michael J.
Publicado em 2014