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Mitochondrial survivin – an Achilles’ heel in cancer chemoresistance
The metabolic shift from oxidative phosphorylation to glycolysis as a hallmark of highly aggressive cancer was postulated by Otto Warburg in the 1920s. We identified baculoviral IAP repeat-containing 5 (BIRC5, also known as survivin) as a key player in mitochondrial metabolism and our recent finding...
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| Опубликовано в: : | Mol Cell Oncol |
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| Главные авторы: | , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Taylor & Francis
2015
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4905378/ https://ncbi.nlm.nih.gov/pubmed/27308600 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2015.1076589 |
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