Modulation of Respiration and Mitochondrial Dynamics by SMAC-Mimetics for Combination Therapy in Chemoresistant Cancer

Inhibitor of apoptosis proteins (IAP) are cell death regulators that bind caspases and interfere with apoptotic signalling via death receptors or intrinsic cell death pathways. BIRC4/XIAP is the most potent anti-apoptotic IAP-member and it physically interacts with caspases via its BIR2 and its BIR3...

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Dettagli Bibliografici
Pubblicato in:Theranostics
Autori principali: Hagenbuchner, Judith, Oberacher, Herbert, Arnhard, Kathrin, Kiechl-Kohlendorfer, Ursula, Ausserlechner, Michael J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Ivyspring International Publisher 2019
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6691393/
https://ncbi.nlm.nih.gov/pubmed/31410190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.33758
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